DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and Ttc24

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_766114.1 Gene:Ttc24 / 214191 MGIID:2443841 Length:334 Species:Mus musculus


Alignment Length:264 Identity:57/264 - (21%)
Similarity:98/264 - (37%) Gaps:61/264 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 LKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYF 281
            |:||..        .|.:.|| .::|:|:.......:.|:....|.. .:::..|.:..:|..:.
Mouse    75 LQNLGM--------THNVLGN-YWEAQEFHQKAASLHGSVGQRWEQG-RSFSGLAFSLSQLGDHR 129

  Fly   282 SAISDCQACLQI--DPMNIKAHLRMAEAHNAE----GKHLESLNVYKK---LLDFEPDNAIAKKA 337
            :|.......||.  |..::|...:..|...|.    |:|.::|..||:   |...|| :::.::.
Mouse   130 AAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEP-SSVRERL 193

  Fly   338 VEKLT-SMLGEVAPSSATRLIIEEIDPPQLKTSEPKK-----------------EAEKSEPTVVK 384
            |.||. :|...||.....:.......|.:|:||...|                 |.|.||....|
Mouse   194 VAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEK 258

  Fly   385 KP-EPVV-------------------SAKKPPPIKDYDLAELVKPNRM-VKSNLVSAAEALGNKM 428
            |. |.:|                   |....|..::|..  ::.|.:: |..:...|.||||...
Mouse   259 KEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPF--IIAPKKLRVSRSSTWAKEALGRNF 321

  Fly   429 QASK 432
            |.::
Mouse   322 QRTR 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 12/67 (18%)
TPR repeat 229..257 CDD:276809 6/27 (22%)
TPR repeat 262..293 CDD:276809 4/30 (13%)
TPR_11 266..329 CDD:290150 15/71 (21%)
TPR 266..297 CDD:197478 6/32 (19%)
TPR repeat 298..326 CDD:276809 9/34 (26%)
Ttc24NP_766114.1 TPR 1 35..68
TPR repeat 38..66 CDD:276809
TPR_12 68..144 CDD:290160 15/78 (19%)
TPR 2 72..105 8/38 (21%)
TPR repeat 72..100 CDD:276809 8/33 (24%)
TPR repeat 111..141 CDD:276809 4/30 (13%)
TPR 3 112..145 5/33 (15%)
TPR_12 113..183 CDD:290160 15/69 (22%)
TPR 4 152..185 8/32 (25%)
TPR_1 152..184 CDD:278916 8/31 (26%)
TPR repeat 152..180 CDD:276809 7/27 (26%)
TPR_12 158..214 CDD:290160 15/56 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 220..258 9/37 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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