DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spag1 and F32D1.3

DIOPT Version :9

Sequence 1:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_504200.1	Gene:	F32D1.3 / 178832	WormBaseID:	WBGene00017983	Length:	774	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	48/216 - (22%)
Similarity:	83/216 - (38%)	Gaps:	51/216 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 NEERDQEQREK-----IISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGN 237
            ||..|::..||     |..||..|..|              .|.||               :|.|
Worm   598 NELGDEQSAEKFFGKAIGENHVNSYLT--------------MAHLK---------------IRQN 633

  Fly   238 ESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHL 302
            .||   |.||.:.:   ::...|| :|....|.|:|...::.|..::...:..|.:||.::.:..
Worm   634 RSF---EVENLLRK---AMTLAPE-SVTVLQNIALAEFHMQNYNRSLLFYRKALHLDPTHLDSLQ 691

  Fly   303 RMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKK---AVEKLTSMLGEVAPSSATRLIIEEIDPP 364
            .:|........|:||...|:|:::.:|::..|..   |:..|..............||   :||
Worm   692 GIANLLQQTQNHVESETFYRKVMEAQPNSYAAHANYGAILHLNQKYDLALKEYEIALI---LDP- 752

  Fly   365 QLKTSEPKKEAEKSEPTVVKK 385
               ||:..:|..|....::::
Worm   753 ---TSDVARENRKKVIRILRR 770

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	15/65 (23%)
		TPR repeat	229..257	CDD:276809	7/27 (26%)
		TPR repeat	262..293	CDD:276809	6/30 (20%)
		TPR_11	266..329	CDD:290150	13/62 (21%)
		TPR	266..297	CDD:197478	7/30 (23%)
		TPR repeat	298..326	CDD:276809	6/27 (22%)
F32D1.3	NP_504200.1	DUF1736	244..316	CDD:369859
		TPR repeat	436..464	CDD:276809
		TPR	448..748	CDD:223533	40/185 (22%)
		TPR repeat	469..498	CDD:276809
		TPR repeat	504..531	CDD:276809
		TPR repeat	537..578	CDD:276809
		TPR repeat	587..614	CDD:276809	5/15 (33%)
		TPR repeat	619..647	CDD:276809	12/62 (19%)
		TPR repeat	655..681	CDD:276809	4/25 (16%)
		TPR repeat	686..716	CDD:276809	6/29 (21%)
		TPR repeat	721..748	CDD:276809	3/26 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900