Protein Alignment Spag1 and spag

DIOPT Version :10

• Sequence 1: NP_651514.1
• Gene: Spag1 / 43239
• FlyBaseID: FBgn0039463
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_315121.5
• Gene: spag / 1275840
• VectorBaseID: AGAMI1_014059
• Length: 693
• Species: Anopheles gambiae
• Alignment Length: 504
• Identity: 100/504 - (19%)
• Similarity: 188/504 - (37%)
• Gaps: 151/504 - (29%)

  Fly    54 RCAEEKLKALKPDSKLFRYEEQIKQSTDLDKTELKPILDWTDAIKTKDNALNE-LKKVKQNLNLP 117
            :| |:..|::|   :|:.:|||:|.:.             |..::..||:..: |..|:.::...
Mosquito    13 KC-EQMQKSIK---ELYEWEEQMKSAN-------------TAKVQPADNSEKKALPPVRSDVKAM 60

  Fly   118 S-----VRKLSKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRK--------WDKYDPD 169
            |     |..|.|.| |.||::.|.|....|.......||:.::  .:|::        .|.|..:
Mosquito    61 SKFSEDVASLEKQD-EAESESAKKKMMADAEILKERGNKQCKL--GNYQEAIELYTQAIDTYGDN 122

  Fly   170 EE--------ILRMDLNEERDQEQREKIISNHSKSVTTD----KLQSERDSLYER---------- 212
            ..        .:.:||.:|        .:::.|.|:..|    |....|...|||
Mosquito   123 AGYYSNRALCYMNLDLFDE--------CLADCSTSIEKDPKYVKAYYRRMQAYERLGESEKAAAE 179

  Fly   213 -------------LQAQLKNLSQLEK--------------------------------EQFAERH 232
                         |.|..::|:::||                                :|.|:::
Mosquito   180 CRQILQLSQDESELNATKRDLARIEKRLSDANSQKGASSPGKEKPPKGAKMDPMLALVKQEADKY 244

  Fly   233 RLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMN 297
            :..||:....|::|.|...|:.:|....:.|:: |.||::.:..||.|...::||...:|:|...
Mosquito   245 KELGNKHLARKDFEKAERSYSKAISLFGDEAIY-YTNRSLCYWNLKDYDKCLADCNKAIQLDENY 308

  Fly   298 IKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDN---AIAKKAVEKLTSMLGEVAPSSATRLIIE 359
            .:.:.|..:.....|.:..::...:|.::...|:   ..|:|.:::|..::....|:... .:..
Mosquito   309 FRPYYRRMQVRELRGAYQSAVEDCRKFIELTKDDKQKQTAEKDLQRLERLVKSEQPAKQA-FVWS 372

  Fly   360 EI-----------DPPQLKTSEPKKEAEKSEPTVVKKPEPVVSAKKPPPIKDYDLAE-------- 405
            ||           .||.|::.:|.......:  |:..|..:.|...|||.:...:.:
Mosquito   373 EIKKNAKLIKFIQKPPHLRSKKPLTRIPIKD--VIPCPIAIDSRVLPPPSQRKSIPDAAIDKMFN 435

  Fly   406 ------LVKPNRMVKSNLVSAAEALGNKMQASKGGAPKKPQSPPMTPKE 448
                  ||:|...:  ||.....|..||:        :...|||.||.|
Mosquito   436 NNTGERLVEPKEEI--NLEHLFPAHSNKL--------RNLFSPPTTPTE 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	NlpI	<229..373	CDD:443815	33/157 (21%)
		TPR repeat	229..257	CDD:276809	7/27 (26%)
		TPR repeat	262..293	CDD:276809	9/30 (30%)
		TPR repeat	298..326	CDD:276809	3/27 (11%)
spag	XP_315121.5	None