DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spag1 and fkbpl

DIOPT Version :9

Sequence 1:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_001923918.1	Gene:	fkbpl / 100149636	ZFINID:	ZDB-GENE-030131-4744	Length:	361	Species:	Danio rerio

Alignment Length:	189	Identity:	41/189 - (21%)
Similarity:	76/189 - (40%)	Gaps:	59/189 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 DEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERLQ-AQLKNLSQLEKEQFAERH 232
            ||.:...:.||:.|:::.|...|.:..::..::.::.:..|:..|. .||| |.||.|.:
Zfish   226 DETLKEDEENEDEDEDEDEGAESPNDSTIPNEEYKTVKAELHCNLSLCQLK-LGQLGKSK----- 284

  Fly   233 RLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMN 297
                :.|.||.|             .:|::....|.:.                 |||||:
Zfish   285 ----DSSIKATE-------------LNPKSTKAWYRHG-----------------QACLQL---- 311

  Fly   298 IKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKKAVEKLTSMLGEVAPSSATRL 356
                          |:..||...:.|:|:.:||:|.|:.|::::.|.|.::......||
Zfish   312 --------------GELEESRMAFGKILELQPDSASARTALKQVNSKLKDLDSKLGQRL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	11/65 (17%)
		TPR repeat	229..257	CDD:276809	4/27 (15%)
		TPR repeat	262..293	CDD:276809	5/30 (17%)
		TPR_11	266..329	CDD:290150	11/62 (18%)
		TPR	266..297	CDD:197478	6/30 (20%)
		TPR repeat	298..326	CDD:276809	4/27 (15%)
fkbpl	XP_001923918.1	TPR_11	263..329	CDD:290150	25/123 (20%)
		TPR repeat	264..292	CDD:276809	12/37 (32%)
		TPR repeat	297..327	CDD:276809	11/64 (17%)
		TPR_8	299..330	CDD:289924	11/65 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900