DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spag1 and ifit11

DIOPT Version :9

Sequence 1:NP_651514.1 Gene:Spag1 / 43239 FlyBaseID:FBgn0039463 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001177393.1 Gene:ifit11 / 100001239 ZFINID:ZDB-GENE-121214-302 Length:483 Species:Danio rerio


Alignment Length:388 Identity:83/388 - (21%)
Similarity:140/388 - (36%) Gaps:98/388 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 AHVEKCTNAREM---EKIVQILRSGEEG------HYPDLQRCAEEKLKALKPD-----------S 67
            :::.|.....||   |.:.::|  ||:|      .|....|..|...||::.|           :
Zfish   119 SYLVKLQKIHEMFPAESVPEVL--GEKGWAYLKFSYKYYDRAVEAFQKAVELDPENSEWNAGYAT 181

  Fly    68 KLFRYEEQIKQSTDLDKTELKPILDWTDAIKTKDN-ALNELK-KVKQNLNLPSVRKLSKIDL--- 127
            .|:|.|           |.|.|.....|.....|: |:.:|: .:..|.:..|:|.|..:.|   
Zfish   182 ALYRIE-----------TALNPFRTEMDTPCIVDSPAIKQLRLAISINPDDDSLRALLGLRLFLC 235

  Fly   128 EKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISN 192
            .|:...|..|....|.:.|.......|..:..:|.....|...|:|...|     |:.......:
Zfish   236 SKKLMKESEKLMETALNGSPEHPHVTRYVAKFFRNQGSVDRSIELLETAL-----QKSPNSGFIH 295

  Fly   193 HSKSV--TTDK--LQSERDSLYERLQAQLKNLSQLEKE----------------QFAERHRLRGN 237
            |..::  .|.|  ||.|:...::...|:.:.:..|||.                |:.|:|.|...
Zfish   296 HQLAMCYKTKKIDLQKEKGDRHQINNARNQCIYYLEKATSLKDSFIIAMCELAMQYGEKHELSKA 360

  Fly   238 ESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFS-----AISDCQACLQIDPMN 297
            |....|.:..|.|:..|..|      ||.|      :.:.::|.:     ||...:.||.::|  
Zfish   361 EGLFKKTFITAKEKNECIHI------VHCY------YAEFQQYSNRCELLAIEHYKKCLTMNP-- 411

  Fly   298 IKAHLRMAEAHNAEGKH--LESLNVYKKLLDFEPDNAIAKKAV----EKLTSMLGEVAPSSAT 354
                      .::||..  .:.:|:.||.|...|:|..|.:.:    :|...|.|:....:.|
Zfish   412 ----------DSSEGNRSAYKLMNIAKKHLKANPNNWDAHEILGLIYQKKGEMFGDTKSYAGT 464

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spag1NP_651514.1 TPR_11 229..295 CDD:290150 17/70 (24%)
TPR repeat 229..257 CDD:276809 8/27 (30%)
TPR repeat 262..293 CDD:276809 8/35 (23%)
TPR_11 266..329 CDD:290150 13/69 (19%)
TPR 266..297 CDD:197478 7/35 (20%)
TPR repeat 298..326 CDD:276809 5/29 (17%)
ifit11NP_001177393.1 TPR_12 54..129 CDD:290160 1/9 (11%)
TPR repeat 55..83 CDD:276809
TPR repeat 97..127 CDD:276809 1/7 (14%)
TPR_2 137..172 CDD:285020 10/36 (28%)
TPR repeat 137..167 CDD:276809 9/31 (29%)
TPR repeat 172..217 CDD:276809 10/55 (18%)
TPR repeat 224..251 CDD:276809 6/26 (23%)
TPR repeat 291..336 CDD:276809 10/44 (23%)
TPR repeat 341..366 CDD:276809 5/24 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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