DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets97D and ERF

DIOPT Version :9

Sequence 1:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_006485.2	Gene:	ERF / 2077	HGNCID:	3444	Length:	548	Species:	Homo sapiens

Alignment Length:	101	Identity:	53/101 - (52%)
Similarity:	68/101 - (67%)	Gaps:	0/101 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 YTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEK 399
            |....|..:.|:|||.|:||:|...|:..||.|.|..|||.:.|||.||||||.:|.||.|||:|
Human    16 YKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDK 80

  Fly   400 LSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGY 435
            |||||||||:..::.|..||||.|||:.:..:|:.|
Human    81 LSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNY 116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472
		SAM_PNT-GABP-alpha	184..272	CDD:176084
		ETS	345..429	CDD:197710	49/83 (59%)
ERF	NP_006485.2	ETS	26..111	CDD:197710	49/84 (58%)
		Atrophin-1	<126..383	CDD:331285
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	130..169
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	184..225
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..304
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	342..478
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	492..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810