DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets97D and ets2

DIOPT Version :9

Sequence 1:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_001120533.1	Gene:	ets2 / 100145687	XenbaseID:	XB-GENE-6084129	Length:	471	Species:	Xenopus tropicalis

Alignment Length:	455	Identity:	138/455 - (30%)
Similarity:	187/455 - (41%)	Gaps:	134/455 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 IRKRINIADVLKPTE--AALAALAEEVVGQLSPPETASQKSSSSESPIKTPLKRMHKEDSEEESV 172
            ::::....:|..||.  :.|.:..||.....:..::.|..|||.|.|:.||..:.....:.:::.
Frog    23 LKRQFAFDNVSVPTSLYSGLFSAYEEEQAVPTGLDSYSHDSSSCELPLLTPCSKAVMSQALKDTF 87

  Fly   173 EGKDVKPVLNWVLDSKFKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQE 237
            .|              |.:|:.||.||.....|...||..||.||.|:|.|..:|...:.|||.|
Frog    88 NG--------------FTKERCRLCIPGNPWLWDENHVFQWLLWAAKEFSLENVNFQKFLMNGHE 138

  Fly   238 LCAMTHEEFNQKLPRDPGNIFWTHL-QLLKE--------------------------CNF-VSVV 274
            ||::..|.|....|...|:|.|.|| :::||                          .|| ...:
Frog   139 LCSLGKERFLALAPDFVGDILWEHLEEMMKEHQVKAQESYIDHSNRDSVNQWMNADSLNFPADPL 203

  Fly   275 HKRAEEQRKPK-------------QPRI-------------------------------MSANSI 295
            ...|:....||             ||.:                               |:|...
Frog   204 QCGAQVHNYPKNGMFNDMCSVPTGQPLLTPKQEFQQYPSSCLKSRAVNYPPSQDFARSNMNALLS 268

  Fly   296 STNSG----------GSLSLEQ-RIMRKSY---------QSVKSSDSVESTTSS--------MNP 332
            |.|||          |:.|.|. ..|.:|:         |.|.|.||.|...|.        |:.
Frog   269 SLNSGKLRDYDSGDSGTESFESTESMLQSWTSQSSLVDMQRVPSYDSFEEDGSQALCLNKPPMSF 333

  Fly   333 SNY------------------TTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDP 379
            .:|                  ...|...:|.:||||||||:|||......|.|.|...|||||||
Frog   334 KDYIQDRCEPAELGKPVIPASILAGFTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLTDP 398

  Fly   380 DRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGYDANELSTLV 444
            |.|||.||::||||.||||||||.||||||.::|.|.||||:.|:|.|||..|:||..:||..::
Frog   399 DEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLHNLLGYTPDELHAML 463

Fly 445 444
Frog 464 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472	1/12 (8%)
		SAM_PNT-GABP-alpha	184..272	CDD:176084	35/115 (30%)
		ETS	345..429	CDD:197710	54/83 (65%)
ets2	NP_001120533.1	SAM_superfamily	85..173	CDD:301707	34/101 (34%)
ets2	NP_001120533.1	ETS	364..449	CDD:197710	55/84 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920