DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ro and hoxc6b

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_005172831.1	Gene:	hoxc6b / 58045	ZFINID:	ZDB-GENE-000822-1	Length:	228	Species:	Danio rerio

Alignment Length:	204	Identity:	57/204 - (27%)
Similarity:	78/204 - (38%)	Gaps:	57/204 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 HSDGGSVSSPDISISDERTSLAAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYV 143
            |.:.|....|.::||...        ||...|...|....:|.....:..:.|...::.
Zfish    13 HLNSGQEVLPSVAISSTN--------YDPVRHFSPYGAAVAQNRIYSNPFYSHQENVMF------ 63

  Fly   144 SPPPAIAAGGAANP-------------VLP----------------HAFPAGFPSDPHFSAGFSA 179
                     |::.|             |||                :|...|...:|..|.....
Zfish    64 ---------GSSRPYDYGSNMFYQDKDVLPSCRQGFGQTQGSLTQDYASDQGKTMEPKGSVQIYP 119

  Fly   180 FLARRRRKEG-----RQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWF 239
            ::.|.....|     .:||.|..:|..|||.||.|||.|.|::|.||.|:|.||.|:|.||||||
Zfish   120 WMQRMNSHSGVGYGSDRRRGRQIYSRYQTLELEKEFHYNRYLTRRRRIEIANTLCLSERQIKIWF 184

  Fly   240 QNRRAKDKR 248
            ||||.|.|:
Zfish   185 QNRRMKWKK 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	31/50 (62%)
hoxc6b	XP_005172831.1	Homeobox	140..192	CDD:278475	32/51 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000