DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and hoxc9a

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_571603.3	Gene:	hoxc9a / 58043	ZFINID:	ZDB-GENE-000328-5	Length:	270	Species:	Danio rerio

Alignment Length:	230	Identity:	64/230 - (27%)
Similarity:	89/230 - (38%)	Gaps:	71/230 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 ISISDERTSL----AAYPAYDFYGHAKDYPQHPSQQHQQH---HHHHHHPPQL---VHQKLSYVS 144
            ||.|...|.|    |.||:..|......:....:..|.|.   :|.:.|.|.|   .....|::.
Zfish    44 ISSSSRPTPLVPECADYPSCSFAPKPPVFTTSWAPVHSQSSVVYHPYTHQPHLGTDSRYVRSWLE 108

  Fly   145 PPPAIAA--GGAANP----VLPHAFPAGFPSDPHFSAG---------------FSAFLARRRRK- 187
            |.|...:  |.|.|.    :.|..|     .||.  ||               .||...|.:::
Zfish   109 PIPGTVSFPGYAGNSRHYGLKPDTF-----QDPR--AGDCLGSNGRTYTDYLYCSAVDIREKQQN 166

  Fly   188 ----------EGRQ----------------------RRQRTTFSTEQTLRLEVEFHRNEYISRSR 220
                      .|:.                      |::|..::..|||.||.||..|.|::|.|
Zfish   167 TPSPETESLSSGKHKDDKAELDPNNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDR 231

  Fly   221 RFELAETLRLTETQIKIWFQNRRAKDKRIEKAQID 255
            |:|:|..|.|||.|:||||||||.|.|::.|.:.|
Zfish   232 RYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKND 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	28/50 (56%)
hoxc9a	NP_571603.3	Hox9_act	11..189	CDD:398350	31/151 (21%)
hoxc9a	NP_571603.3	HOX	202..251	CDD:197696	24/48 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000