DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and Hoxb5

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001178854.1	Gene:	Hoxb5 / 497987	RGDID:	1562292	Length:	269	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	69/225 - (30%)
Similarity:	89/225 - (39%)	Gaps:	55/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PQRPSSPRQFFERLYGHLETRSSE-----NGEIDVGTHAHKPPPCDTPYHSDGGSVSSPDISISD 94
            |.....||  |.:........|.|     ||:    :|..||            |.|||    ||
  Rat    77 PASAQEPR--FRQATSSCSLSSPESLPCTNGD----SHGAKP------------SASSP----SD 119

  Fly    95 ERT---SLAAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAAN 156
            :.|   |.|.:...| ...|...|:..:.             ||....|:...|.|...:..|..
  Rat   120 QATPASSSANFTEID-EASASSEPEEAAS-------------QLSSPSLARAQPEPMATSTAAPE 170

  Fly   157 PVLPHAFPAGFPSDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRR 221
            ...|..||  :....|.|...:.       .:|  :|.||.::..|||.||.|||.|.|::|.||
  Rat   171 GQTPQIFP--WMRKLHISHDMTG-------PDG--KRARTAYTRYQTLELEKEFHFNRYLTRRRR 224

  Fly   222 FELAETLRLTETQIKIWFQNRRAKDKRIEK 251
            .|:|..|.|:|.||||||||||.|.|:..|
  Rat   225 IEIAHALCLSERQIKIWFQNRRMKWKKDNK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	30/50 (60%)
Hoxb5	NP_001178854.1	PRK07003	<67..>171	CDD:235906	29/129 (22%)
Hoxb5	NP_001178854.1	Homeobox	198..251	CDD:365835	31/52 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900