DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and hoxc8a

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001005771.1	Gene:	hoxc8a / 449648	ZFINID:	ZDB-GENE-990415-114	Length:	250	Species:	Danio rerio

Alignment Length:	176	Identity:	63/176 - (35%)
Similarity:	75/176 - (42%)	Gaps:	44/176 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 YGHAKDYP--QHPSQQHQQHHHHH----HHPPQLVHQKLSYVSPPPAIAAGGAAN-----PVLP- 160
            |||....|  ||||...|...||.    .:|        .|...|.|:|..|.|.     ..||
Zfish    40 YGHGAAAPGFQHPSHHVQDFFHHGTTGISNP--------GYQQNPCALACHGDATKFYGYEALPR 96

  Fly   161 --------HAFPAGFP-------SDP-----HFSAGFSAFLA---RRRRKEGRQRRQRTTFSTEQ 202
                    .|..|.:|       ::|     |.|...|..|.   .|....|| |..|.|:|..|
Zfish    97 QPLYGTQQEATLAQYPDCKSSNSTNPGEGQGHLSQNSSPSLMFPWMRPHAPGR-RNGRQTYSRYQ 160

  Fly   203 TLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKR 248
            ||.||.||..|.|::|.||.|::..|.|||.|:||||||||.|.|:
Zfish   161 TLELEKEFLFNPYLTRKRRIEVSHALSLTERQVKIWFQNRRMKWKK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	29/50 (58%)
hoxc8a	NP_001005771.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..152		10/40 (25%)
		Antp-type hexapeptide. /evidence=ECO:0000255	138..143		0/4 (0%)
		Homeobox	153..205	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..250		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900