DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ro and Hoxc9

DIOPT Version :9

Sequence 1:NP_524521.1 Gene:ro / 43234 FlyBaseID:FBgn0003267 Length:350 Species:Drosophila melanogaster
Sequence 2:NP_001094377.1 Gene:Hoxc9 / 368178 RGDID:1595784 Length:260 Species:Rattus norvegicus


Alignment Length:273 Identity:73/273 - (26%)
Similarity:101/273 - (36%) Gaps:81/273 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 PGIKRSDSLDPIANTTILSVPQRPSSPR-QFFERLYGHLETRSSENGEIDVGTHAHKPPP---CD 75
            |...|...|.|..:    ..|....:|: ..|...:..:.::||      |..|.:.|.|   .|
  Rat    35 PAAARPSGLVPDCS----DFPSCSFAPKPAVFSTSWAPVPSQSS------VVYHPYGPQPHLGAD 89

  Fly    76 TPYHSD-----GGSVSSPDISISDERTSLA--AYP---AYDFYGHAKDYPQHPSQQHQQHHHHHH 130
            |.|...     .|:||.|.........:|.  |||   |....|..:.||.:             
  Rat    90 TRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGDGRSYPDY------------- 141

  Fly   131 HPPQLVHQKLSYVSPPPAIAAGGAANPVLPHAFPAGFPSDPHFSAGFSAFLARRRRKEGR----- 190
                      .|.||       |......|...|:     |...|     ||..:.||.:     
  Rat   142 ----------MYGSP-------GELRDRAPQTLPS-----PEADA-----LAGSKHKEEKADLDP 179

  Fly   191 ------------QRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRR 243
                        .|::|..::..|||.||.||..|.|::|.||:|:|..|.|||.|:||||||||
  Rat   180 SNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRR 244

  Fly   244 AKDKRIEKAQIDQ 256
            .|.|::.|.:.|:
  Rat   245 MKMKKMNKEKTDK 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
roNP_524521.1 Homeobox 196..247 CDD:278475 28/50 (56%)
Hoxc9NP_001094377.1 Hox9_act 1..179 CDD:398350 40/193 (21%)
HOX 192..241 CDD:197696 24/48 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
22.000

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