Protein Alignment ro and PDX1

DIOPT Version :9

• Sequence 1: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_000200.1
• Gene: PDX1 / 3651
• HGNCID: 6107
• Length: 283
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 82/253 - (32%)
• Similarity: 98/253 - (38%)
• Gaps: 58/253 - (22%)

  Fly    71 PPPCDTPYHSDGGSV---SSPDISISDERTSLAAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHP 132
            |||...|:....|::   |.|||| ..|...||..||.                   .|.|||.|
Human    43 PPPPPHPFPGALGALEQGSPPDIS-PYEVPPLADDPAV-------------------AHLHHHLP 87

  Fly   133 PQLVHQKLSYVSPPPAIAAGGAANPVL--PHAFPAGFP----SDPHFSAGFSAFLARRRRKEGRQ 191
            .|     |:...||......||...||  |:.....||    :..|...|..|..|.....| ..
Human    88 AQ-----LALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPE-EN 146

  Fly   192 RRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQ 256
            :|.||.::..|.|.||.||..|:||||.||.|||..|.|||..|||||||||.|.|   |.:..:
Human   147 KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWK---KEEDKK 208

  Fly   257 HYRNFVVANGFMSS-------IMGQAATTMPPGGVTGGVAVGVGLNYYAAAATPAALP 307
            ......|..|.::.       ..|:....:||....||             |.|.|.|
Human   209 RGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGG-------------AVPPAAP 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	31/50 (62%)
PDX1	NP_000200.1	Transactivation domain. /evidence=ECO:0000250	13..73		11/30 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..71		11/28 (39%)
		Antp-type hexapeptide	118..123		2/4 (50%)
		Homeobox	149..202	CDD:278475	32/52 (62%)
		Nuclear localization signal. /evidence=ECO:0000250	197..203		4/8 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..283		13/69 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810