Protein Alignment ro and HOXD4

DIOPT Version :9

• Sequence 1: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 65/234 - (27%)
• Similarity: 87/234 - (37%)
• Gaps: 87/234 - (37%)

  Fly    70 KPPPCD------------TPYHSDGGSVSSPDISISDERTSLAAYPAYDF--------------- 107
            |.|||:            ..|:  ||.....|..      ....||..||
Human    16 KFPPCEEYLQGGYLGEQGADYY--GGGAQGADFQ------PPGLYPRPDFGEQPFGGSGPGPGSA 72

  Fly   108 ---YGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAA----NPVLPHAFPA 165
               .||.:: |..|...:.........||          :||||...|..|    :|..|   |:
Human    73 LPARGHGQE-PGGPGGHYAAPGEPCPAPP----------APPPAPLPGARAYSQSDPKQP---PS 123

  Fly   166 G---------FP---------SDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHR 212
            |         :|         .:|:::.             |..:|.||.::.:|.|.||.|||.
Human   124 GTALKQPAVVYPWMKKVHVNSVNPNYTG-------------GEPKRSRTAYTRQQVLELEKEFHF 175

  Fly   213 NEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEK 251
            |.|::|.||.|:|.||.|:|.||||||||||.|.|:..|
Human   176 NRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHK 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	30/50 (60%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		24/117 (21%)
		Antp-type hexapeptide	133..138		1/4 (25%)
		Homeobox	157..210	CDD:306543	31/52 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900