Protein Alignment ro and HOXC4

DIOPT Version :9

• Sequence 1: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 80/323 - (24%)
• Similarity: 108/323 - (33%)
• Gaps: 124/323 - (38%)

  Fly    70 KPPPCD-------TPYHSDGGSVSSPDISISDERTSLAAYPAYDFYG----------HAKDYPQH 117
            |.|||:       .|.||.                        ::||          |.:.||..
Human    16 KFPPCEEYSQNSYIPEHSP------------------------EYYGRTRESGFQHHHQELYPPP 56

  Fly   118 P--------------------SQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAANPVLPHA 162
            |                    |:.|......||||    .:..|...|.|...|..:.:|. |.|
Human    57 PPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHP----EKSQSLCEPAPLSGASASPSPA-PPA 116

  Fly   163 FPAGFPSDPHFSAGFSAFLARRRRK-----------EGRQRRQRTTFSTEQTLRLEVEFHRNEYI 216
            .....|..|..:|.....:....:|           .|..:|.||.::.:|.|.||.|||.|.|:
Human   117 CSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYL 181

  Fly   217 SRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVANGFMSSIMGQAATTMPP 281
            :|.||.|:|.:|.|:|.||||||||||.|.|:      |....|..|.:.             ||
Human   182 TRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK------DHRLPNTKVRSA-------------PP 227

  Fly   282 GGVTGGVAVGVGLNYYAAAATPAALPKDNTQDANFIDIDDQFQRQQQQKQQQQQQQQRRRETT 344
            .|.....         .:||||.. .:|::|.|.                  ..:|||..:.|
Human   228 AGAAPST---------LSAATPGT-SEDHSQSAT------------------PPEQQRAEDIT 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	29/50 (58%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		26/139 (19%)
		Antp-type hexapeptide	135..140		0/4 (0%)
		Homeobox	159..213	CDD:395001	30/53 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		17/90 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900