Protein Alignment ro and HOXB8

DIOPT Version :10

• Sequence 1: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 66/216 - (30%)
• Similarity: 86/216 - (39%)
• Gaps: 64/216 - (29%)

  Fly    36 QRPSSPRQFFERLYGHLETRSSENGEIDVGTHAHKPPPCDTPYHSDGGSVSSPDISISDERTSLA 100
            |.||..::|:             :|...:.|..::..||....|.|.|
Human    49 QHPSQIQEFY-------------HGPSSLSTAPYQQNPCAVACHGDPG----------------- 83

  Fly   101 AYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQ---KLSYVSPPPAIAAGGAANPVLPHA 162
                 :|||:  |..|..|....|       .|.||..   ||:..|.....|.|...:|.....
Human    84 -----NFYGY--DPLQRQSLFGAQ-------DPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQL 134

  Fly   163 FPAGFPSDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAET 227
            ||.   ..|..:||         |:.|||     |:|..|||.||.||..|.|::|.||.|::..
Human   135 FPW---MRPQAAAG---------RRRGRQ-----TYSRYQTLELEKEFLFNPYLTRKRRIEVSHA 182

  Fly   228 LRLTETQIKIWFQNRRAKDKR 248
            |.|||.|:||||||||.|.|:
Human   183 LGLTERQVKIWFQNRRMKWKK 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	29/51 (57%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/7 (29%)
		Homeodomain	147..203	CDD:459649	32/60 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		0/1 (0%)