Protein Alignment ro and HOXB2

DIOPT Version :9

• Sequence 1: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 92/348 - (26%)
• Similarity: 119/348 - (34%)
• Gaps: 128/348 - (36%)

  Fly    11 PDGSPGIKRSDSLDPIANTTILSVPQRPSSPRQFFERLYGHLETRSSENGEIDVGTHAHKPPPCD 75
            |...|..:...||.|.|:|.     |||.|.::             :|:|..     ...|||..
Human    44 PPPPPFEQTFPSLQPGASTL-----QRPRSQKR-------------AEDGPA-----LPPPPPPP 85

  Fly    76 TPYHSDGGSVSSPDISISDERTSLAAYPAYDF-YGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQK 139
            .|                      ||.||.:| :...|...:.|||
Human    86 LP----------------------AAPPAPEFPWMKEKKSAKKPSQ------------------- 109

  Fly   140 LSYVSPPP---AIAAGGAANPVLPHAFPAGFPSDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTE 201
             |..||.|   |:.|.|..:|    |...|.|     .||           .|..||.||.::..
Human   110 -SATSPSPAASAVPASGVGSP----ADGLGLP-----EAG-----------GGGARRLRTAYTNT 153

  Fly   202 QTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVANG 266
            |.|.||.|||.|:|:.|.||.|:|..|.|||.|:|:||||||.|.||  :.|..:.........|
Human   154 QLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR--QTQHREPPDGEPACPG 216

  Fly   267 FMSSIMGQA------------------ATTMPPGGVTGGVAV----------GVGLN------YY 297
            .:..|...|                  |...||..|.|.::.          |.|.:      ..
Human   217 ALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLAVRLEGAGASSPGCALRG 281

  Fly   298 AAAATPAALPKD---NTQDANFI 317
            |....|..||:|   ..||:.|:
Human   282 AGGLEPGPLPEDVFSGRQDSPFL 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	28/50 (56%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		39/182 (21%)
		Antp-type hexapeptide	94..99		1/4 (25%)
		Homeobox	147..199	CDD:278475	29/51 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		7/44 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810