DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and Hoxb3

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001100512.1	Gene:	Hoxb3 / 303488	RGDID:	1310780	Length:	429	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	68/272 - (25%)
Similarity:	91/272 - (33%)	Gaps:	99/272 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 ERTSLAAYPAYDFY----GHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSP---------- 145
            :.|:.|.:..|..|    |...|.|..|..|...|....:.......|.|...:|
  Rat     8 DNTAAALFGGYSSYPGSNGFGYDGPPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGS 72

  Fly   146 -------PPAIAAGGAANPVLPHAFP---------AGFPS---DPHFSAGFSAFLARR---RRKE 188
                   |..:.|...:.|  |.|.|         .|.||   .|...|..::.|.::   ..||
  Rat    73 CMRPGLAPEPLPAPPGSPP--PSAAPTSTTSNSNNGGGPSKSGPPKCGASSNSTLTKQIFPWMKE 135

  Fly   189 GRQ-------------------------------------------------RRQRTTFSTEQTL 204
            .||                                                 :|.||.:::.|.:
  Rat   136 SRQTSKLKNSSPGTAEGCGGGGGGGGGGGSSSGGGGSGGGGGDKSPPGSAASKRARTAYTSAQLV 200

  Fly   205 RLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVANGFMS 269
            .||.|||.|.|:.|.||.|:|..|.|:|.||||||||||.|.|:.:||:            |..|
  Rat   201 ELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAK------------GLAS 253

  Fly   270 SIMGQAATTMPP 281
            |..|.:....||
  Rat   254 SSGGPSPAGSPP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	28/50 (56%)
Hoxb3	NP_001100512.1	Homeobox	191..244	CDD:395001	29/52 (56%)
Hoxb3	NP_001100512.1	DUF4074	365..427	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810