DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and hoxb2a

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_571191.1	Gene:	hoxb2a / 30338	ZFINID:	ZDB-GENE-990415-103	Length:	390	Species:	Danio rerio

Alignment Length:	141	Identity:	54/141 - (38%)
Similarity:	65/141 - (46%)	Gaps:	18/141 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PSQQHQQHHHH-------HHHPPQLVHQKLSYVSPPP-AIAAGGAANPVLPHA--FPAGFPSDPH 172
            |..||||....       .|..|.:..:|.|...|.| |.||..||:|....:  ..||..|...
Zfish    83 PPTQHQQGPAPLSGGAPLAHEFPWMKEKKSSKKCPKPGATAAAAAASPSQASSGYTTAGLESPTE 147

  Fly   173 FSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKI 237
            ...|..        .....||.||.::..|.|.||.|||.|:|:.|.||.|:|..|.|||.|:|:
Zfish   148 IQGGLD--------NVSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKV 204

  Fly   238 WFQNRRAKDKR 248
            ||||||.|.||
Zfish   205 WFQNRRMKHKR 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	28/50 (56%)
hoxb2a	NP_571191.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..73
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..100		5/16 (31%)
		Antp-type hexapeptide	103..108		1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	108..155		14/54 (26%)
		Homeobox	162..214	CDD:278475	29/51 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..338		3/5 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810