Protein Alignment ro and Hoxa1

DIOPT Version :10

• Sequence 1: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_037207.2
• Gene: Hoxa1 / 103690132
• RGDID: 11414885
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 240
• Identity: 76/240 - (31%)
• Similarity: 100/240 - (41%)
• Gaps: 73/240 - (30%)

  Fly    38 PSSPRQFFERLYGHLETRSSENGEIDV-GTHAHKPPPCDTPYHSDGGSVSSPDISISDERTSLAA 101
            ||...|.|...||..    ..|.|.|| |.:    |||....:|  |::|||.:
  Rat    96 PSYGAQNFSAPYGPY----GLNQEADVSGGY----PPCAPAVYS--GNLSSPMV----------- 139

  Fly   102 YPAYDFYGHAKDYPQHPSQQHQQHHHHHH-------HPPQLVHQKLSYVSPPPAIAAGGAANPVL 159
                                  ||||||.       ..||.:|.  ||.....::|.....|.:.
  Rat   140 ----------------------QHHHHHQGYAGGTVGSPQYIHH--SYGQEHQSLALATYNNSLS 180

  Fly   160 P-HA-------FPAGFPSDPHFSAGFSAFLARRRRKE----------GRQRRQRTTFSTEQTLRL 206
            | ||       .||...|.|  :..|.....:|...:          |:....||.|:|:|...|
  Rat   181 PLHASHQEACRSPASETSSP--AQTFDWMKVKRNPPKTGKVGEYGYVGQPNAVRTNFTTKQLTEL 243

  Fly   207 EVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEK 251
            |.|||.|:|::|:||.|:|.:|:|.|||:||||||||.|.|:.||
  Rat   244 EKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	30/51 (59%)
Hoxa1	NP_037207.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..82
		Interaction with OGT. /evidence=ECO:0000250|UniProtKB:P09022	74..202		39/152 (26%)
		COG5576	175..>285	CDD:227863	42/111 (38%)
		Antp-type hexapeptide	203..208		1/4 (25%)
		Homeodomain	232..285	CDD:459649	31/52 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..334		5/9 (56%)