DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ro and Hoxa4

DIOPT Version :9

Sequence 1:NP_524521.1 Gene:ro / 43234 FlyBaseID:FBgn0003267 Length:350 Species:Drosophila melanogaster
Sequence 2:NP_077326.1 Gene:Hoxa4 / 100912525 RGDID:2814 Length:285 Species:Rattus norvegicus


Alignment Length:290 Identity:81/290 - (27%)
Similarity:110/290 - (37%) Gaps:79/290 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 GSPDGSPGIKRSDSLDPIANTTILSVPQRPS--SPRQFFERLYGHLETRSSENGEIDVGTHAHKP 71
            |...|.||..|..|...:......:..|.|:  :||......:|.|                :..
  Rat    34 GGVGGGPGYPRPQSSPHLPAPNPHAARQTPAYYAPRAREPSYHGGL----------------YPA 82

  Fly    72 PPCDTPYHSDGGSVSSPDISISDERTSLAAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLV 136
            |....||...|.|.:.|:.|           ||..  .|....||.|:            ||   
  Rat    83 PAAACPYACRGASPARPEQS-----------PAPG--AHPSPAPQPPA------------PP--- 119

  Fly   137 HQKLSYVSPPPAIAAGGAANPVLPHAFPAGFPSDP--------------HFSAGFSAFLARRRRK 187
             ::.:.....||:|.||:| |..|.......|:.|              |.||...::      .
  Rat   120 -RRCAPGPTTPAVATGGSA-PACPLLLADQGPAGPKGKEPVVYPWMKKIHVSAVNPSY------N 176

  Fly   188 EGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKA 252
            .|..:|.||.::.:|.|.||.|||.|.|::|.||.|:|.||.|:|.|:||||||||.|.|:..| 
  Rat   177 GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHK- 240

  Fly   253 QIDQHYRNFVVANGFMSSIMGQAATTMPPG 282
                      :.|..|.|....:|...|||
  Rat   241 ----------LPNTKMRSSNPASAPAGPPG 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
roNP_524521.1 Homeobox 196..247 CDD:278475 29/50 (58%)
Hoxa4NP_077326.1 Homeobox 183..236 CDD:278475 30/52 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
22.000

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