DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and mnx1

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_002935225.2	Gene:	mnx1 / 100496534	XenbaseID:	XB-GENE-919890	Length:	338	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	82/270 - (30%)
Similarity:	103/270 - (38%)	Gaps:	93/270 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SPDGSPGIKRSDSL------------------------DPIANTTILSVPQRPSSPRQFFERLYG 50
            |..|||..:.:|||                        .|| |...|.....|..|.|   .|||
Frog    37 SNSGSPPSEHTDSLRTDTPSPPRTCGLVPKPGFLSSHQHPI-NMMALHPQAAPGIPPQ---ALYG 97

  Fly    51 HLETRSSENGEIDVGTHAHKPPPCDTPYHSDGGSVSSPDISISDERTSLAAYPAYDFYGHAKDYP 115
            |.....|....:..|.|                    |.:|          ||          ||
Frog    98 HPMYSYSAAAALAAGQH--------------------PALS----------YP----------YP 122

  Fly   116 QHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAANPVLPHAFPAG--FPSDPHFSAGFS 178
            |      .|..||.|||..           |..|:||.........|..||  .|....|::...
Frog   123 Q------MQGAHHAHHPVD-----------PIKISAGTFQLDQWLRASTAGMMLPKMADFNSQAQ 170

  Fly   179 AFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRR 243
            :.|.      |:.||.||.|:::|.|.||.:|..|:|:||.:|||:|.:|.|||||:||||||||
Frog   171 SNLL------GKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRR 229

  Fly   244 AKDKRIEKAQ 253
            .|.||.:||:
Frog   230 MKWKRSKKAK 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	30/50 (60%)
mnx1	XP_002935225.2	Homeobox	180..234	CDD:395001	31/53 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910