DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ro and hoxa3

DIOPT Version :9

Sequence 1:	NP_524521.1	Gene:	ro / 43234	FlyBaseID:	FBgn0003267	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001120901.1	Gene:	hoxa3 / 100151729	XenbaseID:	XB-GENE-482267	Length:	406	Species:	Xenopus tropicalis

Alignment Length:	283	Identity:	78/283 - (27%)
Similarity:	105/283 - (37%)	Gaps:	88/283 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LYGHLETRSSENGEIDVGTHAHKPPP---CDTPYHSDGGSVSSP----------DISISDERTSL 99
            :||....:.: ||.....:....||.   .:|.||....|:.||          ||:.|..||
Frog    12 IYGGYPYQGA-NGFTYNASQQQYPPSSSLLETEYHRPACSLQSPGSAVPHHKANDINESCMRT-- 73

  Fly   100 AAYPAYDFYGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAI--------AAGGAAN 156
                   ....:...|..|.||         ..||         .|||::        ||..::|
Frog    74 -------INSQSNQAPVIPEQQ---------PTPQ---------GPPPSVSPPQTTSNAATASSN 113

  Fly   157 -------PVL-PHAFP-------------AGFPSDPHFSAGFSAFLARRRRKEGRQRRQRTTFST 200
                   |.: ...||             ||..|.....||     .:....:...:|.||.:::
Frog   114 KATSITSPTMSKQIFPWMKESRQNTKQQKAGSSSSGESCAG-----DKSPPGQSSSKRARTAYTS 173

  Fly   201 EQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVAN 265
            .|.:.||.|||.|.|:.|.||.|:|..|.|||.||||||||||.|.|:.:|.:
Frog   174 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK------------ 226

  Fly   266 GFMSSIMGQAATTMP-PGGVTGG 287
            ..|:|..||:....| |....||
Frog   227 SMMTSSGGQSPCRSPVPTPSVGG 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ro	NP_524521.1	Homeobox	196..247	CDD:278475	29/50 (58%)
hoxa3	NP_001120901.1	Homeobox	168..221	CDD:395001	30/52 (58%)
hoxa3	NP_001120901.1	DUF4074	344..404	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910