DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rb97D and hnrnpd

DIOPT Version :9

Sequence 1:	NP_001014671.1	Gene:	Rb97D / 43231	FlyBaseID:	FBgn0004903	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001103930.1	Gene:	hnrnpd / 560522	ZFINID:	ZDB-GENE-070424-97	Length:	314	Species:	Danio rerio

Alignment Length:	299	Identity:	91/299 - (30%)
Similarity:	140/299 - (46%)	Gaps:	74/299 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EEDDICELEHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGFITYTKSLM 85
            |||:       .|:|:|||:..||:::||.::.::|:|||..:..|..|.|||||||:.:.::..
Zfish    50 EEDE-------GKMFVGGLSWDTTKKDLKDYFTKFGEVVDCTLKLDPLTGRSRGFGFVLFKEAES 107

  Fly    86 VDRAQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHDEECLREYFLQFGNVV 150
            |::....:.|.::||.::.|:|      ::.:|...|||:|||||..:..||.:||||..:|.|.
Zfish   108 VEKVITQKEHKLNGKVIDPKKA------KAMKTKEPVKKIFVGGLSPDTPEEKIREYFDAYGEVE 166

  Fly   151 SVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVKKSIYNLDKKEKQQPGGLAN 215
            |::|..:..|.|||||.|:.|.:.:.|.|.:.|..|.|.....:||.::      .|:|
Zfish   167 SIELPMENKTNKRRGFCFITFKEEEPVKKIMEKMYHNIGLSKCEVKVAM------SKEQ------ 219

  Fly   216 AIKPSLNQQQQQQGG---------GQQPPNGNMQAPSFRPPVPPQQAMGPYQQQPPPAPMSAPPP 271
                  .|||||.||         |:..||.|.           .|..|.|..|        ...
Zfish   220 ------YQQQQQWGGRGGYTSRGRGRGGPNQNW-----------NQGYGNYWNQ--------GYG 259

  Fly   272 NFNYWGPPPPAMPPYYQQPPPQQMNGWGPYPPPQQNGWN 310
            |:..:|        |..|       |:|.|.....:|:|
Zfish   260 NYGNYG--------YNNQ-------GYGGYGGYDYSGYN 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rb97D	NP_001014671.1	RRM1_hnRNPA_like	33..110	CDD:241022	28/76 (37%)
Rb97D	NP_001014671.1	RRM2_hnRNPA_like	124..196	CDD:240774	29/71 (41%)
hnrnpd	NP_001103930.1	CBFNT	3..54	CDD:285369	3/10 (30%)
		RRM1_hnRNPD_like	56..129	CDD:241019	26/72 (36%)
		RRM2_hnRNPD	140..214	CDD:241027	31/73 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910