DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rb97D and dazap1

DIOPT Version :9

Sequence 1:	NP_001014671.1	Gene:	Rb97D / 43231	FlyBaseID:	FBgn0004903	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	XP_012815264.1	Gene:	dazap1 / 448406	XenbaseID:	XB-GENE-856469	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	469	Identity:	150/469 - (31%)
Similarity:	201/469 - (42%)	Gaps:	123/469 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGFITYTKSLMVDRAQENR 93
            :.:.|||:|||...||:|.|:.::.|:|:|||.|:|:|..|.:||||||:.:.....|.....:|
Frog     7 DEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASR 71

  Fly    94 PHIIDGKTVEAKRALPR---PERE----------SRETNISVKKLFVGGLKDNHDEECLREYFLQ 145
            ||.:||:.::.|...||   |||.          .|..|....|:||||:..|..|..|||||.:
Frog    72 PHTLDGRNIDPKPCTPRGMQPERTRPREGWQQKGPRTENSRSNKIFVGGIPHNCGETELREYFKR 136

  Fly   146 FGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVKKSIYNLDKKEKQQP 210
            ||.|..|.::.|....:.|||.|:.|:|..:||:|:....|.|....|:||:: ...|.| .|.|
Frog   137 FGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRA-EPRDSK-SQTP 199

  Fly   211 GGLANAIKPSLNQ------QQQQQGGGQQPPNGNMQAPSFRPPVPPQQAMGPYQQ--------QP 261
            |      .|..||      |....|...|||      |:::....||....|..|        ..
Frog   200 G------PPGSNQWGGRAMQSTANGWTGQPP------PTWQQSYSPQGMWMPTGQTIVFSTGGYG 252

  Fly   262 PPAPMSAPPPNFNYWGPPPPAMPPYYQQPPPQQMNGWGPYPPPQ--QNGWNAPPP------PPPG 318
            |||....|        ||||:..|:.....|      |.:||||  ..|:..|||      |||
Frog   253 PPAGRGGP--------PPPPSFAPFLVSTTP------GAFPPPQGFPPGYATPPPFGYGYGPPP- 302

  Fly   319 AQQWHANQWGCPPPVQQVPPVGAVPPPMGHNGPPPTAPGNWNMPPPVPG------AAPPSHQQQS 377
                       |||.|.|.  ..||||.|..|..|.|     .|||.||      :.|||.||..
Frog   303 -----------PPPDQFVS--SGVPPPPGTPGAAPLA-----FPPPPPGQSAQDLSKPPSGQQDF 349

  Fly   378 SQQPTPQPNFG---TGYQQNYGGGPSKHNNMNANRMNPYSAGPPNSYHTPQPPAYTGYNAGPLPP 439
               |..|..:|   :||.|::         .:.|:..||::||..                  |.
Frog   350 ---PFSQFGYGQDMSGYGQSF---------PDLNQQPPYTSGPST------------------PA 384

  Fly   440 NGSVPPPTGAKAVG 453
            :|.  ||.|...:|
Frog   385 SGG--PPAGGSGLG 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rb97D	NP_001014671.1	RRM1_hnRNPA_like	33..110	CDD:241022	32/76 (42%)
Rb97D	NP_001014671.1	RRM2_hnRNPA_like	124..196	CDD:240774	29/71 (41%)
dazap1	XP_012815264.1	RRM1_DAZAP1	11..92	CDD:241018	34/80 (43%)
dazap1	XP_012815264.1	RRM2_DAZAP1	112..191	CDD:240773	31/79 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56786
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920