DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rb97D and HNRNPAB

DIOPT Version :9

Sequence 1:NP_001014671.1 Gene:Rb97D / 43231 FlyBaseID:FBgn0004903 Length:471 Species:Drosophila melanogaster
Sequence 2:NP_112556.2 Gene:HNRNPAB / 3182 HGNCID:5034 Length:332 Species:Homo sapiens


Alignment Length:317 Identity:93/317 - (29%)
Similarity:145/317 - (45%) Gaps:79/317 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 DVIVLADREEDDICELEHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGF 77
            |.|..:..|||       ..|:|:|||:..|::::||.::.::|:|||..:..|..|.|||||||
Human    58 DQINASKNEED-------AGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGF 115

  Fly    78 ITYTKSLMVDRAQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHDEECLREY 142
            |.:..:..|::..:.:.|.:||:.::.|:|:...:.       .|||:|||||.....||.:|||
Human   116 ILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKD-------PVKKIFVGGLNPEATEEKIREY 173

  Fly   143 FLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVK----KSIYNLD 203
            |.:||.:.:::|..|....|||||.|:.|.:.:.|.|.:.||.|.:.....::|    |.:|   
Human   174 FGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVY--- 235

  Fly   204 KKEKQQPGGLANAIKPSLNQQQQQQGGGQQPPNGNMQAPSFRPPVPPQQAMGPYQQQPPPAPMSA 268
            ::::...||..|.     |:..:..|||   ..|..|:.|:      .|..|             
Human   236 QQQQYGSGGRGNR-----NRGNRGSGGG---GGGGGQSQSW------NQGYG------------- 273

  Fly   269 PPPNFNYWGPPPPAMPPY-YQQPPPQQMNGWGP------YPPPQQNGWNAPPPPPPG 318
                 |||.      ..| |||       |:||      |.|....|:.      ||
Human   274 -----NYWN------QGYGYQQ-------GYGPGYGGYDYSPYGYYGYG------PG 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rb97DNP_001014671.1 RRM1_hnRNPA_like 33..110 CDD:241022 28/76 (37%)
RRM2_hnRNPA_like 124..196 CDD:240774 28/71 (39%)
HNRNPABNP_112556.2 CBFNT 1..70 CDD:311868 5/18 (28%)
RRM1_hnRNPAB 66..145 CDD:410151 30/85 (35%)
RRM2_hnRNPAB 150..229 CDD:409997 31/85 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1202220at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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