Protein Alignment Rb97D and HNRNPAB

DIOPT Version :10

• Sequence 1: NP_524520.1
• Gene: Rb97D / 43231
• FlyBaseID: FBgn0004903
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_112556.2
• Gene: HNRNPAB / 3182
• HGNCID: 5034
• Length: 332
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 93/317 - (29%)
• Similarity: 145/317 - (45%)
• Gaps: 79/317 - (24%)

  Fly    13 DVIVLADREEDDICELEHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGF 77
            |.|..:..|||       ..|:|:|||:..|::::||.::.::|:|||..:..|..|.|||||||
Human    58 DQINASKNEED-------AGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGF 115

  Fly    78 ITYTKSLMVDRAQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHDEECLREY 142
            |.:..:..|::..:.:.|.:||:.::.|:|:...:.       .|||:|||||.....||.:|||
Human   116 ILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKD-------PVKKIFVGGLNPEATEEKIREY 173

  Fly   143 FLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVK----KSIYNLD 203
            |.:||.:.:::|..|....|||||.|:.|.:.:.|.|.:.||.|.:.....::|    |.:|
Human   174 FGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVY--- 235

  Fly   204 KKEKQQPGGLANAIKPSLNQQQQQQGGGQQPPNGNMQAPSFRPPVPPQQAMGPYQQQPPPAPMSA 268
            ::::...||..|.     |:..:..|||   ..|..|:.|:      .|..|
Human   236 QQQQYGSGGRGNR-----NRGNRGSGGG---GGGGGQSQSW------NQGYG------------- 273

  Fly   269 PPPNFNYWGPPPPAMPPY-YQQPPPQQMNGWGP------YPPPQQNGWNAPPPPPPG 318
                 |||.      ..| |||       |:||      |.|....|:.      ||
Human   274 -----NYWN------QGYGYQQ-------GYGPGYGGYDYSPYGYYGYG------PG 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rb97D	NP_524520.1	RRM2_hnRNPA_like	124..196	CDD:409766	28/71 (39%)
		RRM_SF	33..110	CDD:473069	28/76 (37%)
HNRNPAB	NP_112556.2	CBFNT	1..70	CDD:311868	5/18 (28%)
		RRM1_hnRNPAB	66..145	CDD:410151	30/85 (35%)
		RRM2_hnRNPAB	150..229	CDD:409997	31/85 (36%)