DRSC/TRiP Functional Genomics Resources

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Protein Alignment SPARC and sparcl1

DIOPT Version :10

Sequence 1:NP_651509.2 Gene:SPARC / 43230 FlyBaseID:FBgn0026562 Length:304 Species:Drosophila melanogaster
Sequence 2:NP_001124077.1 Gene:sparcl1 / 567331 ZFINID:ZDB-GENE-060130-6 Length:606 Species:Danio rerio


Alignment Length:380 Identity:96/380 - (25%)
Similarity:148/380 - (38%) Gaps:120/380 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 QASTEFSEDLLDEDLDLSDIDENEEEFLRLLE-------------EKNKIKD------------- 57
            ||..|..|.  :.|::....|:.:|:  .:||             :||:.|.             
Zfish   231 QAQEELKEP--ENDIEKGKNDQQDEK--NILEPGISEGKMAKKDKKKNESKSNGKGKGKKQRNSE 291

  Fly    58 ------------IERENEIA-----TKLAEVQHNL----------------LNPV---------- 79
                        ||...|:|     .|:.|...|.                :|||          
Zfish   292 LLEKMQSDQAGAIEDTEELAQKKDQEKVTEATENTESKPRKKNGKWTRLVGMNPVQIRATMDLYP 356

  Fly    80 ------------VEVDLCETMSCGAGRICQMHDE-KPKCVC--IPECPEEVDTRRLVCTNTNETW 129
                        |..|.||...|..|:.|:::|| ||.|||  ..|||..|:....||...|:|:
Zfish   357 DVRLTRHSNGQGVPADPCENFRCKRGKTCKLNDENKPLCVCQEPTECPPNVNDFEHVCGTDNKTY 421

  Fly   130 PSDCSVYQQRCWCDSGEPGCTNPDNAHMHIDYYGACHEPRSCEGEDLKDFPRRMRDWLFNVMRDL 194
            .|.|.::..:|..:..:.|      ..:|:||.|:|.....|...:|..||.||||||.||:..|
Zfish   422 DSSCHLFATKCGLEGTKLG------HRLHLDYTGSCKFIAPCVESELVQFPLRMRDWLKNVLLQL 480

  Fly   195 AERDELTEHYM--------QMELEAE-----------------TNNSRRWSNAAVWKWCDLD-GD 233
            .|.|.::..::        |...|:|                 ..|...:.....|::..:| ..
Zfish   481 YEHDSMSPGFLTAKQRIRVQKIYESERRLHAGDHPVEILQQDFEKNYNMYIYPVHWQFAQMDQHP 545

  Fly   234 TDRSVSRHELFPIRAPLVSLEHCIAPFLESCDSNKDHRITLVEWGACLELDPEDL 288
            :||.::..||.|:|.|||.:|||.:.|.:.||::||..::..||.:|..:..||:
Zfish   546 SDRFLTHSELAPLRVPLVPMEHCTSVFFQMCDADKDKLVSFKEWCSCFGIKEEDM 600

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPARCNP_651509.2 FSL_SPARC 85..168 CDD:238649 29/85 (34%)
EFh_SPARC_like 171..285 CDD:320010 41/139 (29%)
EF-hand motif 219..251 CDD:320010 9/32 (28%)
EF-hand motif 253..285 CDD:320010 11/31 (35%)
sparcl1NP_001124077.1 MSCRAMM_ClfA <111..328 CDD:468110 19/100 (19%)
KAZAL_FS 373..454 CDD:412159 29/86 (34%)
EFh_SPARC_EC 457..597 CDD:330171 41/139 (29%)
EF-hand motif 530..562 CDD:320015 8/31 (26%)
EF-hand motif 565..595 CDD:320015 11/29 (38%)

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