DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPARC and spock3

DIOPT Version :9

Sequence 1:	NP_001262998.1	Gene:	SPARC / 43230	FlyBaseID:	FBgn0026562	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	XP_009305894.1	Gene:	spock3 / 562002	ZFINID:	ZDB-GENE-090311-24	Length:	389	Species:	Danio rerio

Alignment Length:	235	Identity:	49/235 - (20%)
Similarity:	83/235 - (35%)	Gaps:	62/235 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 DLCETMSCGAGRICQMHD-EKPKCV------------------CIPECPEEVDTRRLVCTNTNET 128
            |.|..:.||..::|...| :.|.||                  | ..||  |.....:|.....|
Zfish    64 DPCLKIKCGRHKVCVAEDYQTPTCVSQRRMSFKDMNLNSPLLKC-KRCP--VVHPSPICGTDGHT 125

  Fly   129 WPSDCSVYQQ--------------RCWCDSGEPGCTNPDNAHMHIDYYGACHEPRSCEGEDLKDF 179
            :.:.|.:..|              :|.|..|.|.                  |.|.|...::.:.
Zfish   126 YSTKCKLEYQACISGKQISVKCPGQCPCAPGNPA------------------EKRECGNAEMTEV 172

  Fly   180 PRRMRDWLFNVMRDLAERDELTEHYMQMELEAETNNSR--RWSNAAVWKWCDLDGDTDRSVSRHE 242
            ..|:|:|:    ..|.|.....:.|...:.|.:.:.|:  ...::..|.:..||.:.|..:.:.|
Zfish   173 VSRLREWI----TVLHESGNTNKKYKFQKPEKKVDMSKVPLCKDSLGWMFSRLDTNFDLHLDQSE 233

  Fly   243 LFPIRAPLVSLEHCIAPFLESCDSNKDHRITLVEWGACLE 282
            |..:.:.  ..:.|...||.|||.|:|..::..||.:|.:
Zfish   234 LSSLNSE--KSDVCTKAFLRSCDPNRDRLVSSQEWCSCFQ 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001262998.1	FSL_SPARC	85..168	CDD:238649	20/115 (17%)
		SPARC_Ca_bdg	169..278	CDD:287550	25/110 (23%)
		SPARC_EC	170..292	CDD:238155	26/115 (23%)
spock3	XP_009305894.1	KAZAL	108..151	CDD:197624	7/44 (16%)
		SPARC_Ca_bdg	162..267	CDD:287550	25/110 (23%)
		SPARC_EC	163..279	CDD:238155	26/115 (23%)
		TY	277..341	CDD:238114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910