DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPARC and agr-1

DIOPT Version :9

Sequence 1:	NP_001262998.1	Gene:	SPARC / 43230	FlyBaseID:	FBgn0026562	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001022152.3	Gene:	agr-1 / 3565243	WormBaseID:	WBGene00018304	Length:	1473	Species:	Caenorhabditis elegans

Alignment Length:	156	Identity:	38/156 - (24%)
Similarity:	61/156 - (39%)	Gaps:	37/156 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 NKIKDIER----------ENEIATK--------LAEVQHNLLNPVVEVDLCETM-SCGAGRICQM 98
            |:.:|:.|          :||...|        :.:|:|   .....:.:|.|. ||...::|.:
Worm   403 NRCEDVMRPVCATNGETFDNECEMKKKSCETKSMIKVKH---QGTCGIGVCATFDSCKKPQVCVV 464

  Fly    99 HDEKPKCVCIPECPEEVDTRRLVCTNTNETWPSDCSVYQQRCWCDSG-----EPGCTNPDNAHMH 158
            .|.|||||| |.|.:|.   :.||.:..:|:.::|.:....|.....     ...|.........
Worm   465 VDGKPKCVC-PSCTDEF---KEVCGSDGKTYSNECRLQNAACMAQKNIFVKYNSACEACKLKKEK 525

  Fly   159 IDYYGAC----HEPRSCEGEDLKDFP 180
            .|:|.||    :|...|:..|  |.|
Worm   526 CDFYSACVVGENEKAECKCPD--DCP 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001262998.1	FSL_SPARC	85..168	CDD:238649	25/92 (27%)
		SPARC_Ca_bdg	169..278	CDD:287550	4/12 (33%)
		SPARC_EC	170..292	CDD:238155	4/11 (36%)
agr-1	NP_001022152.3	KAZAL	172..220	CDD:197624
		KAZAL	251..301	CDD:197624
		KAZAL	327..371	CDD:197624
		KAZAL	400..445	CDD:197624	8/44 (18%)
		KAZAL	472..516	CDD:197624	10/47 (21%)
		KAZAL	547..592	CDD:197624	2/3 (67%)
		KAZAL	612..660	CDD:197624
		EGF_Lam	670..716	CDD:238012
		EGF_Lam	722..>759	CDD:238012
		KAZAL	<819..852	CDD:197624
		LamG	1081..1236	CDD:238058
		LamG	1289..1450	CDD:238058
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910