DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SPARC and Fstl4

DIOPT Version :9

Sequence 1:NP_001262998.1 Gene:SPARC / 43230 FlyBaseID:FBgn0026562 Length:304 Species:Drosophila melanogaster
Sequence 2:NP_796033.2 Gene:Fstl4 / 320027 MGIID:2443199 Length:841 Species:Mus musculus


Alignment Length:240 Identity:48/240 - (20%)
Similarity:74/240 - (30%) Gaps:88/240 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 CETMSCGAGRICQMH--DEKPKCVCIPEC-PEEVDTRRLVCTNTNETWPSDC------------- 133
            |....|..|..|.::  ..:|.|.|:..| |..:.    ||.:....:.:.|             
Mouse    64 CGKKLCSHGSRCLLNRTTGQPSCQCLEVCRPRYMP----VCGSDGRLYGNHCELRRAACLLGKRI 124

  Fly   134 -SVYQQRCWCDSGEPGCTNPDNAHMHIDYYGACHEPRSCEGEDLKDFPRRMRDWLFNVM------ 191
             ||:.:.|:. .|:. ||....|                          |:::.|..:.      
Mouse   125 VSVHSKDCFL-KGDM-CTMAGYA--------------------------RLKNVLLALQSRRQPL 161

  Fly   192 ------RDLAERDELTEHYMQMELEAETNNSRRWSNAA--VWKWCDLDGDTDRSVSRHELFPIRA 248
                  :.||.:..|....:..:|:|:.|........|  |.|..|:||                
Mouse   162 PQGTPRQSLASQKRLLVESLFKDLDADGNGHLGSLELAQYVLKEQDMDG---------------- 210

  Fly   249 PLVSLEHCI-APFLESCDSNKDHRITLVEWGAC-----LELDPED 287
               ||..|. :..|...|.|.|..:||.|:...     |.|.|||
Mouse   211 ---SLNRCSPSDLLRFDDYNSDGSLTLGEFYTAFQVIQLSLAPED 252

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPARCNP_001262998.1 FSL_SPARC 85..168 CDD:238649 19/99 (19%)
SPARC_Ca_bdg 169..278 CDD:287550 24/123 (20%)
SPARC_EC 170..292 CDD:238155 29/138 (21%)
Fstl4NP_796033.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 29..54
KAZAL_FS 92..132 CDD:238052 7/43 (16%)
EFh 178..242 CDD:298682 19/82 (23%)
EF-hand_7 178..241 CDD:290234 19/81 (23%)
IG_like 255..322 CDD:214653
Ig 266..322 CDD:143165
I-set 340..429 CDD:254352
Ig2_Follistatin_like 357..432 CDD:143213
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.