DRSC/TRiP Functional Genomics Resources

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Protein Alignment SPARC and Sparcl1

DIOPT Version :9

Sequence 1:NP_001262998.1 Gene:SPARC / 43230 FlyBaseID:FBgn0026562 Length:304 Species:Drosophila melanogaster
Sequence 2:NP_037078.2 Gene:Sparcl1 / 25434 RGDID:2531 Length:634 Species:Rattus norvegicus


Alignment Length:305 Identity:85/305 - (27%)
Similarity:126/305 - (41%) Gaps:68/305 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 EFSEDLLDEDLDLSDIDENEEEFLRLLEEKNKIKDIERENEIATKLAEVQHNLLNPVVE------ 81
            ::.|:..||..:.|:..:|:                      ..|.||...| ..|..|      
  Rat   357 KYGEETPDESENRSEAGDNQ----------------------GAKKAESSPN-AEPSDEGNSRGH 398

  Fly    82 -VDLCETMSCGAGRICQMHDE-KPKCVCIPECPEEVDTRRLV---CTNTNETWPSDCSVYQQRCW 141
             .|.|....|..|..|:.... ||.|||  :.||.....:::   |...|:|:.|.|.::..:|.
  Rat   399 SADSCMNFQCKRGHTCKTDQHGKPHCVC--QDPETCPPAKILDQACGTDNQTYASSCHLFATKCM 461

  Fly   142 CDSGEPGCTNPDNAHMHIDYYGACHEPRSCEGEDLKDFPRRMRDWLFNVMRDLAE---------- 196
            .:..:.|      ..:.:||:|||....:|...::..||.||||||.|::..|.|          
  Rat   462 LEGTKKG------HQLQLDYFGACKSIPACTDFEVAQFPLRMRDWLKNILMQLYEPNPKHGGYLN 520

  Fly   197 -----------RDE----LTEHYMQMELEAETNNSRRWSNAAVWKWCDLD-GDTDRSVSRHELFP 245
                       .||    ..:|.:::.|.....|...:.....|::.:|| ...||.::..||.|
  Rat   521 EKQRSKVKKIYLDEKRLLAGDHPIELLLRDFKKNYHMYVYPVHWQFNELDQHPADRILTHSELAP 585

  Fly   246 IRAPLVSLEHCIAPFLESCDSNKDHRITLVEWGACLELDPEDLKE 290
            :||.||.:||||..|.|.||.|||..|||.|||.|..:..||:.|
  Rat   586 LRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDE 630

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPARCNP_001262998.1 FSL_SPARC 85..168 CDD:238649 23/86 (27%)
SPARC_Ca_bdg 169..278 CDD:287550 44/134 (33%)
SPARC_EC 170..292 CDD:238155 50/147 (34%)
Sparcl1NP_037078.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..335
MSCRAMM_ClfB <95..402 CDD:411414 11/67 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 360..398 11/60 (18%)
KAZAL_FS 403..482 CDD:412159 23/86 (27%)
EFh_SPARC_SPARCL1 485..625 CDD:320015 47/139 (34%)
EF-hand motif 558..590 CDD:320015 10/31 (32%)
EF-hand motif 593..623 CDD:320015 18/29 (62%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166352945
Domainoid 1 1.000 76 1.000 Domainoid score I8741
eggNOG 1 0.900 - - E1_KOG4004
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H3438
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1528521at2759
OrthoFinder 1 1.000 - - FOG0003487
OrthoInspector 1 1.000 - - otm45391
orthoMCL 1 0.900 - - OOG6_105759
Panther 1 1.100 - - LDO PTHR13866
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X2378
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1312.710

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