DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPARC and Fstl5

DIOPT Version :9

Sequence 1:	NP_001262998.1	Gene:	SPARC / 43230	FlyBaseID:	FBgn0026562	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001240648.1	Gene:	Fstl5 / 213262	MGIID:	2442179	Length:	847	Species:	Mus musculus

Alignment Length:	172	Identity:	36/172 - (20%)
Similarity:	66/172 - (38%)	Gaps:	29/172 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 CETMSCGAGRICQMHDE--KPKCVCIPECPEEVDTRRLVCTNTNETWPSDCSVYQQRCW------ 141
            ||...||.||.|.::.|  ..:|.|:..|.:..   :.||.:..|.:.:.|.|::..|.
Mouse    65 CENKYCGLGRHCVINRETRHAECACMDLCKQHY---KPVCGSDGEFYENHCEVHRAACLKKQKIT 126

  Fly   142 ------CDSGEPGCTNPDNAHMH---IDYYGACHEPRSCEGEDLKDFPRR--MRDWLFNVM---- 191
                  |......|...:.:.|.   :|.....:..:..|..:..|..|:  :.|.:|...
Mouse   127 IVHNEDCFFEGDNCMAIEYSKMKSMLLDLQNQKYITQENENPNSDDISRKKPLVDQMFKYFDADS 191

  Fly   192 RDLAERDELTEHYMQMELEAETNNSRRWSNAAVWKWCDLDGD 233
            ..|.:.:|||:...|.||..:.::...:.   :.|:.|.:.|
Mouse   192 NGLVDINELTQVIKQEELNKDLSDCTLYD---LLKYDDFNAD 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001262998.1	FSL_SPARC	85..168	CDD:238649	21/99 (21%)
		SPARC_Ca_bdg	169..278	CDD:287550	15/71 (21%)
		SPARC_EC	170..292	CDD:238155	15/70 (21%)
Fstl5	NP_001240648.1	KAZAL_FS	93..133	CDD:238052	7/42 (17%)
		EF-hand_7	182..243	CDD:372618	11/52 (21%)
		Ig	266..323	CDD:319273
		Ig2_Follistatin_like	358..433	CDD:143213
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910