DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPARC and Spock1

DIOPT Version :9

Sequence 1:	NP_001262998.1	Gene:	SPARC / 43230	FlyBaseID:	FBgn0026562	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_033288.2	Gene:	Spock1 / 20745	MGIID:	105371	Length:	442	Species:	Mus musculus

Alignment Length:	305	Identity:	65/305 - (21%)
Similarity:	104/305 - (34%)	Gaps:	81/305 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DLLDEDLDLSDI-------------DENEEEFLRLLEEKNKIKDIERENEIATKLAEVQHNLLNP 78
            :.||.|..||.:             ||.|:::.|   ..|..|..::              .|:|
Mouse    37 NFLDNDQWLSTVSQYDRDKYWNRFRDEVEDDYFR---NWNPNKPFDQ--------------ALDP 84

  Fly    79 VVEVDLCETMSCGAGRICQMHD-EKPKCV---------------------------CIPECPEEV 115
              ..|.|..:.|...::|...| :...||                           |.| ||  |
Mouse    85 --SKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAHKHWLGPSNLVKCKP-CP--V 144

  Fly   116 DTRRLVCTNTNETWPSDCSVYQQRC--------WCDSGEPGCTNPDNAHMHIDYYGACHEPRSCE 172
            ....:||.:...|:.|.|.:....|        .||...|....|:......       |..:|.
Mouse   145 AQSAMVCGSDGHTYTSKCKLEFHACSTGKSLNSLCDGPCPCLPEPEPLKPKA-------EKSACT 202

  Fly   173 GEDLKDFPRRMRDWLFNVMRDLAERDELTEHYMQMELEAETNNSRRWSNAAVWKWCDLDGDTDRS 237
            .::|::...|::|| |..:.:.|.|..........:...:|:......::..|.:..||.:.|..
Mouse   203 DKELRNLASRLKDW-FGALHEDANRVIKPTSSDPAQGRFDTSILPICKDSLGWMFNKLDMNYDLL 266

  Fly   238 VSRHELFPIRAPLVSLEHCIAPFLESCDSNKDHRITLVEWGACLE 282
            :...|:..|.  |...|.||.|...||||.||.:::..||..|.:
Mouse   267 LDHSEINAIY--LDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQ 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001262998.1	FSL_SPARC	85..168	CDD:238649	21/118 (18%)
		SPARC_Ca_bdg	169..278	CDD:287550	27/108 (25%)
		SPARC_EC	170..292	CDD:238155	29/113 (26%)
Spock1	NP_033288.2	KAZAL	140..181	CDD:197624	11/43 (26%)
		SPARC_Ca_bdg	199..305	CDD:287550	27/108 (25%)
		SPARC_EC	200..318	CDD:238155	29/113 (26%)
		TY	315..376	CDD:238114
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	375..395
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	420..442
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910