Protein Alignment SPARC and Sparcl1

DIOPT Version :10

• Sequence 1: NP_651509.2
• Gene: SPARC / 43230
• FlyBaseID: FBgn0026562
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_034227.3
• Gene: Sparcl1 / 13602
• MGIID: 108110
• Length: 650
• Species: Mus musculus
• Alignment Length: 236
• Identity: 74/236 - (31%)
• Similarity: 109/236 - (46%)
• Gaps: 38/236 - (16%)

  Fly    85 CETMSCGAGRICQMHDE-KPKCVCIPECPEEVDTRRLV---CTNTNETWPSDCSVYQQRCWCDSG 145
            |....|..|.||:...: ||.|||  :.||.....:::   |...|:|:.|.|.::..:|..:..
Mouse   419 CTNFQCKRGHICKTDPQGKPHCVC--QDPETCPPAKILDQACGTDNQTYASSCHLFATKCRLEGT 481

  Fly   146 EPGCTNPDNAHMHIDYYGACHEPRSCEGEDLKDFPRRMRDWLFNVMRDLAE-------------- 196
            :.|      ..:.:||:|||....:|...::..||.||||||.|::..|.|
Mouse   482 KKG------HQLQLDYFGACKSIPACTDFEVAQFPLRMRDWLKNILMQLYEPNPKHGGYLNEKQR 540

  Fly   197 -------RDE----LTEHYMQMELEAETNNSRRWSNAAVWKWCDLD-GDTDRSVSRHELFPIRAP 249
                   .||    ..:|.:::.|.....|...:.....|::.:|| ...||.::..||.|:||.
Mouse   541 SKVKKIYLDEKRLLAGDHPIELLLRDFKKNYHMYVYPVHWQFNELDQHPADRILTHSELAPLRAS 605

  Fly   250 LVSLEHCIAPFLESCDSNKDHRITLVEWGACLELDPEDLKE 290
            ||.:||||..|.|.||.|||..|||.|||.|..:..||:.|
Mouse   606 LVPMEHCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_651509.2	FSL_SPARC	85..168	CDD:238649	24/86 (28%)
		EFh_SPARC_like	171..285	CDD:320010	47/139 (34%)
		EF-hand motif	219..251	CDD:320010	10/32 (31%)
		EF-hand motif	253..285	CDD:320010	18/31 (58%)
Sparcl1	NP_034227.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..352
		2A1904	<212..>413	CDD:273344
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..415
		KAZAL_FS	419..498	CDD:412159	24/86 (28%)
		EFh_SPARC_like	501..641	CDD:320010	47/139 (34%)
		EF-hand motif	574..607	CDD:320010	10/32 (31%)
		EF-hand motif	609..641	CDD:320010	18/31 (58%)