DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPARC and smoc1

DIOPT Version :9

Sequence 1:	NP_001262998.1	Gene:	SPARC / 43230	FlyBaseID:	FBgn0026562	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	XP_012823493.1	Gene:	smoc1 / 100145733	XenbaseID:	XB-GENE-989094	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	237	Identity:	51/237 - (21%)
Similarity:	78/237 - (32%)	Gaps:	71/237 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SCGAGRICQMHDEK--PK-CVCIPEC-PEEVDTRRLVCTNTNETWPSDCSVYQQRCWC---DSGE 146
            ||...|...:.:.|  |: .:.|||| |..:..            |..|......|||   |:|.
Frog   263 SCDQERQSALEEAKLNPRDGIVIPECAPGGLYK------------PVQCHQSTGYCWCVLVDTGR 315

  Fly   147 PGCTNPDNAHMHIDYYGACHEPRSCEGE------DLKDFPRRMRDWLFNVMRDLAE--------- 196
            |           :......:|...||.:      |.:|   ..:|      |:||.
Frog   316 P-----------LPGTSTRYETPVCESDARWKNTDAED---PFKD------RELAGCPEGKKLEF 360

  Fly   197 ----RDELTEHYMQMELEAETNNSRRWS----------NAAVWKWCDLDGDTDRSVSRHELFPIR 247
                .|.||...:|....|......|:|          ...:|.:..||.:....:::.|:.|.:
Frog   361 ITSLLDALTTDMVQAINSAAPAAGGRFSEPDPNHTLEERVVLWYFSQLDSNGSEDINKKEMKPFK 425

  Fly   248 APL---VSLEHCIAPFLESCDSNKDHRITLVEWGACLELDPE 286
            ..:   ...:.|...|.:.||.|||..|:..|...||.:..|
Frog   426 RYVKKKAKPKKCARRFTDYCDLNKDKSISFPELKGCLGVRKE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001262998.1	FSL_SPARC	85..168	CDD:238649	18/85 (21%)
		SPARC_Ca_bdg	169..278	CDD:287550	29/140 (21%)
		SPARC_EC	170..292	CDD:238155	32/149 (21%)
smoc1	XP_012823493.1	KAZAL_FS	47..87	CDD:238052
		Thyroglobulin_1	95..158	CDD:278514
		Thyroglob_assoc	159..256	CDD:293205
		TY	263..329	CDD:238114	19/88 (22%)
		SPARC_EC	<401..468	CDD:238155	17/67 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910