DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment His2Av and h2ax

DIOPT Version :9

Sequence 1:	NP_001262997.1	Gene:	His2Av / 43229	FlyBaseID:	FBgn0001197	Length:	141	Species:	Drosophila melanogaster
Sequence 2:	NP_957367.1	Gene:	h2ax / 394048	ZFINID:	ZDB-GENE-040426-987	Length:	142	Species:	Danio rerio

Alignment Length:	123	Identity:	76/123 - (61%)
Similarity:	93/123 - (75%)	Gaps:	4/123 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAE 65
            |:|  .||..|||:|||.:||:||||||||||:||.|:....:. ||||.|.||.||:|||||||
Zfish     1 MSG--RGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAE-RVGAGAPVYLAAVLEYLTAE 62

  Fly    66 VLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLI-KATIAGGGVIPHIHKSLIGKK 122
            :|||||||::|.|..||.|||||||:|.||||:.|: ..|||.|||:|:|...|:.||
Zfish    63 ILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKK 120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
His2Av	NP_001262997.1	PLN00154	6..121	CDD:177756	72/115 (63%)
h2ax	NP_957367.1	PTZ00017	1..121	CDD:185399	76/123 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		12/22 (55%)
		H2A	6..120	CDD:238029	71/114 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	123..142
		[ST]-Q motif	139..140
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5262
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53554
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820