Protein Alignment His2Av and H2AZ1

DIOPT Version :10

• Sequence 1: NP_524519.1
• Gene: His2Av / 43229
• FlyBaseID: FBgn0001197
• Length: 141
• Species: Drosophila melanogaster
• Sequence 2: NP_002097.1
• Gene: H2AZ1 / 3015
• HGNCID: 4741
• Length: 128
• Species: Homo sapiens
• Alignment Length: 128
• Identity: 122/128 - (95%)
• Similarity: 124/128 - (96%)
• Gaps: 2/128 - (1%)

  Fly     1 MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAE 65
            ||||||||||||||.||||||.|||||||||||||||||||||||||||||||||||||||||||
Human     1 MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAE 65

  Fly    66 VLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKK--EETV 126
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||  ::||
Human    66 VLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV 128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
His2Av	NP_524519.1	PLN00154	6..121	CDD:177756	112/114 (98%)
H2AZ1	NP_002097.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		21/23 (91%)
		Required for interaction with INCENP. /evidence=ECO:0000250	1..17		14/15 (93%)
		PLN00154	6..121	CDD:177756	112/114 (98%)
		M6 cassette	89..100		10/10 (100%)
		Required for interaction with INCENP. /evidence=ECO:0000250	93..103		9/9 (100%)
		Required for interaction with PWWP2A. /evidence=ECO:0000269|PubMed:28645917	120..128		3/7 (43%)