DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ball and Csnk1a1

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_006526446.1	Gene:	Csnk1a1 / 93687	MGIID:	1934950	Length:	374	Species:	Mus musculus

Alignment Length:	386	Identity:	103/386 - (26%)
Similarity:	151/386 - (39%)	Gaps:	73/386 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GQWRIGPSIGVGGFGEIYAACKV--GEKNYDAVVKCEPH-GNGPLFVEMHFYLRNAKLEDIKQFM 106
            |::::...||.|.||:||.|..:  ||   :..||.|.. ...|..      |..:||..|.|
Mouse    15 GKYKLVRKIGSGSFGDIYLAINITNGE---EVAVKLESQKARHPQL------LYESKLYKILQ-- 68

  Fly   107 QKHGLKSLGMPYILANGSVEVNGEK-HRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDV 170
                 ..:|:|:|...|.     || :..:||...|..|........:|....||..||.||:..
Mouse    69 -----GGVGIPHIRWYGQ-----EKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISR 123

  Fly   171 YQYMHSNGYVHADLKAANILLGLEK---------------------------GGAAQAYLVDFGL 208
            .:|:|:..::|.|:|..|.|:|:.:                           .|..|.:|:||||
Mouse   124 IEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSPSQDPSFSGLNQLFLIDFGL 188

  Fly   209 ASHFVTGDFKPDPKKMH---------NGTIEYTSRDAHLGV-PTRRADLEILGYNLIEWLGAELP 263
            |.     .::.:..:.|         .||..|.|.:||||: .:||.|:|.|||.|:.:....||
Mouse   189 AK-----KYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLP 248

  Fly   264 WVTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWF 328
            |...|......|.:|..|..|....|.|    .||.|.....::.|...|...:.|||...|..|
Mouse   249 WQGLKAATKKQKYEKISEKKMSTPVEVL----CKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 309

  Fly   329 SSALKQLKIPNNGDLDFKMKPQTSSNNNLSPPGTSKAATARKAKKIDSPVLNSS--LDEKI 387
            ....:.|....:...|:.|..|.::....|..|..:.|.....|:.|....|..  .|||:
Mouse   310 RILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGIKDEKL 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	89/323 (28%)
		SPS1	47..432	CDD:223589	102/384 (27%)
		Pol_alpha_B_N	<399..>502	CDD:285602
Csnk1a1	XP_006526446.1	STKc_CK1_alpha	16..309	CDD:271030	88/322 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810