DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ball and ckl8

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_199146.1	Gene:	ckl8 / 834350	AraportID:	AT5G43320	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	147/546 - (26%)
Similarity:	224/546 - (41%)	Gaps:	129/546 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GQWRIGPSIGVGGFGEIYAACKV--GEKNYDAVVKCEP-HGNGPLFVEMHFYLRNAKLEDIKQFM 106
            |::::|..:|.|.|||::....|  ||   :..||.|| ....|   ::|:        :.|.:|
plant     7 GKYKLGRKLGSGSFGELFLGVNVQTGE---EVAVKLEPARARHP---QLHY--------ESKLYM 57

  Fly   107 QKHGLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVY 171
            ...|  ..|:|::...|   |.|| :..:|:...|..:........:|....||..||.||::..
plant    58 LLQG--GTGIPHLKWYG---VEGE-YNCMVIDLLGPSMEDLFNYCSRRFNLKTVLMLADQMINRV 116

  Fly   172 QYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHFVTGDFKPD------PKKMHNGTIE 230
            :|||..|::|.|:|..|.|:||.: .|.|.|::|:|||..:  .|.:..      ..|...||..
plant   117 EYMHVRGFLHRDIKPDNFLMGLGR-KANQVYIIDYGLAKKY--RDLQTHRHIPYRENKNLTGTAR 178

  Fly   231 YTSRDAHLGV-PTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTL 294
            |.|.:.|||: .:||.|||.|||.|:.:|...|||   :.|....|.||     .|.|.|. |.|
plant   179 YASVNTHLGIEQSRRDDLESLGYVLMYFLRGSLPW---QGLRAGTKKQK-----YDKISEK-KRL 234

  Fly   295 FP-----KGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMK------ 348
            .|     |..||....:..||..|....:|||...:..|    :.|.|......|:...
plant   235 TPVEVLCKSFPPEFTSYFLYVRSLRFEDKPDYPYLKRLF----RDLFIREGYQFDYVFDWTILKY 295

  Fly   349 PQTSSNNNLSPPGTSKAATARKAKK--IDSPVLNSSLDEKISASEDDEEEEEKS----------- 400
            ||.||       |:|.::..|.:.:  ::.||..:...:|.||....:..:..|
plant   296 PQFSS-------GSSSSSKPRSSLRPAMNPPVPIAERPDKPSAGAGQDSRDRFSGALEAYARRNG 353

  Fly   401 ----------HRKKTAKKVTPSARNAKVSPLKRVADSSPPSQKRVK-----TEPKSTPRE----- 445
                      .|.:|::.|..|::           |::|.:.:||:     |...|:.|:
plant   354 SGSGVVQADRSRPRTSENVLASSK-----------DTTPQNYERVERPISSTRHASSSRKAVVSS 407

  Fly   446 -RATPKAS-PKPRSTPKASPKPQTPTAARLR-TPNAKINFSPSISLRGRPGGKTVINDDLTPQPR 507
             |||..|. .:.||:.......::.||.|.: .|:.....|.|...|..| .:|.  .|:|.|
plant   408 VRATSSADFTENRSSRVVPSNGRSSTAQRTQLVPDPTTRPSSSSFTRAAP-SRTA--RDITLQ-- 467

  Fly   508 SKKTYEFNFELDVSMDANVIVNVKRK 533
                   :|||      ..|.|.|||
plant   468 -------SFEL------LTIGNGKRK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	93/297 (31%)
		SPS1	47..432	CDD:223589	115/428 (27%)
		Pol_alpha_B_N	<399..>502	CDD:285602	27/136 (20%)
ckl8	NP_199146.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	95/309 (31%)
ckl8	NP_199146.1	Pkinase	9..244	CDD:278497	84/266 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810