DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ball and vrk3

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001037922.1	Gene:	vrk3 / 733538	XenbaseID:	XB-GENE-986614	Length:	511	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	99/353 - (28%)
Similarity:	171/353 - (48%)	Gaps:	45/353 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AAAPAK----------KVVSAKKAKSKLYKMPEKVKEGTVFTDLAKGQWRIGPSIGVGGFGEIYA 63
            |::||.          ||...|..|.:|      :.|..:.||....:||:...:.....|.:|.
Frog   172 ASSPASLHGSKSKNSPKVRGVKSVKIEL------LPENEILTDTQSVKWRLAEFLSAWNTGMLYK 230

  Fly    64 ACKVG----EKNYDAVVKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKHGLKSLGMPYILANGS 124
            |.|..    |::|.|.:..:   :|.:|.|.:|:.|.||...:.::.:.|....:|:|..:..|.
Frog   231 AYKTSSAAEEQHYIAKLDAK---DGRIFTEQNFFQRAAKKNIVDKWKKSHSCPLIGIPDCVGFGV 292

  Fly   125 VEVNGEKHRFIVMPRYGSDLTKFL--EQNGKRLPEGTVYRLAIQMLDVYQYMHSNGYVHADLKAA 187
                .|.:||::....|.:|...:  :.:|| |||..::.::.::::..:|:|.|.|||.|:.|.
Frog   293 ----HESYRFLIFSALGQNLQSVIDDDDDGK-LPEKAIFHISYRIINTLEYIHENEYVHGDITAE 352

  Fly   188 NILLGLEKGGAAQAYLVDFGLASHF------VTGDFKPDPKKMHNGTIEYTSRDAHLG-VPTRRA 245
            ||.  :.:...::.||..:..|..:      ||  ::...:..|.||.|:.|.|.|.| .|:||:
Frog   353 NIF--VNRNDPSEVYLAGYYFAFRYCPCGKHVT--YREGGRSPHEGTAEFISEDIHKGAAPSRRS 413

  Fly   246 DLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLF-PKGVPPPIGDFMKY 309
            |||.|||.:::||...|||..|   ..|..:.:.|:.|..||.|.|...| .:..|..:..:::|
Frog   414 DLESLGYCMLKWLCGSLPWSEQ---TNPNTIMEQKKRFKTNIAEFLGQSFKQRKFPDGLRKYLEY 475

  Fly   310 VSKLTHNQEPDYDKCRSWFSSALKQLKI 337
            |..|::.::|||...|:..|.||.::.|
Frog   476 VMNLSYEEKPDYTVLRNTLSCALAKMGI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	86/305 (28%)
		SPS1	47..432	CDD:223589	88/305 (29%)
		Pol_alpha_B_N	<399..>502	CDD:285602
vrk3	NP_001037922.1	zinc_ribbon_2	5..27	CDD:379084
vrk3	NP_001037922.1	PKc_like	203..498	CDD:389743	87/309 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D371612at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010