DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ball and Csnk1g1

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_017451375.1	Gene:	Csnk1g1 / 64086	RGDID:	621404	Length:	467	Species:	Rattus norvegicus

Alignment Length:	524	Identity:	123/524 - (23%)
Similarity:	203/524 - (38%)	Gaps:	130/524 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 WRIGPSIGVGGFGEIYAACKVGEKNYD---AVVKCEP-HGNGP-LFVEMHFYLRNAKLEDIKQFM 106
            :|:|..||.|.|||:    ::|:..|.   ..:|.|| ....| |.:|..||         ||.
  Rat    44 FRVGKKIGCGNFGEL----RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFY---------KQL- 94

  Fly   107 QKHGLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVY 171
               |....|:|.:...|..    .|:..:|:...|..|....:...:.....||..:|||:|...
  Rat    95 ---GSAGEGLPQVYYFGPC----GKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRM 152

  Fly   172 QYMHSNGYVHADLKAANILLGLEKGGAAQ--AYLVDFGLASHFVTGDFKPD-PKKMH---NGTIE 230
            :|:||...::.|:|..|.|:| .:|...:  .:::|||||..::..:.|.. |.:.|   .||..
  Rat   153 EYVHSKNLIYRDVKPENFLIG-RQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 216

  Fly   231 YTSRDAHLG-VPTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAK--------EAFMDN 286
            |.|.:.||| ..:||.|||.||:..:.:|...|||...|...:..:.||..        ||..:|
  Rat   217 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTPIEALCEN 281

  Fly   287 IGESLKTLFPKGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMKPQT 351
            ..|.:.|            :::||.:|...::|||:..|:.|:...::.....:...|:..:|
  Rat   282 FPEEMMT------------YLRYVRRLDFFEKPDYEYLRNLFTDLFERKGYTFDYAYDWVGRP-- 332

  Fly   352 SSNNNLSPPGTSKAATARKAKKIDSPVLNSSLDEKISASEDDEEEEEKSHRKKTAKKVTPSARNA 416
                                  |.:||.:..:|...||.    ..|..:||.:
  Rat   333 ----------------------IPTPVGSVHVDSGASAI----TRESHTHRDR------------ 359

  Fly   417 KVSPLKRVADSSPPSQKRVKTEPKSTPRERATPKASPKPRSTPKASPKPQTPTAARLRTPNAKIN 481
                        |..|:.::.:..|:.|           |...:..|..||.| :.|.:..|...
  Rat   360 ------------PSQQQPLRNQTTSSER-----------RGEWEIQPSRQTNT-SYLTSHLAADR 400

  Fly   482 FSPSISLRGRPGGKTVINDDLTPQPRSKKTYEFNFELDVSMDANVI--VNV--------KRKKKA 536
            ...|:.:.....|:  :|.|......|......:.|::|..:||.:  :|:        ||||.|
  Rat   401 HGGSVQVVSSTNGE--LNVDDPTGAHSSAPITAHAEVEVVEEANCLKMLNLWCCCFFKRKRKKTA 463

  Fly   537 DQDK 540
            .:.|
  Rat   464 QRHK 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	84/300 (28%)
		SPS1	47..432	CDD:223589	97/404 (24%)
		Pol_alpha_B_N	<399..>502	CDD:285602	16/102 (16%)
Csnk1g1	XP_017451375.1	STKc_CK1_gamma	43..331	CDD:271028	86/320 (27%)
Csnk1g1	XP_017451375.1	CK1gamma_C	331..429	CDD:403712	26/163 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740