DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ball and vrk3

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001013586.1	Gene:	vrk3 / 541443	ZFINID:	ZDB-GENE-030131-246	Length:	459	Species:	Danio rerio

Alignment Length:	356	Identity:	94/356 - (26%)
Similarity:	160/356 - (44%)	Gaps:	42/356 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PRVAKPKAAAPAKKVVSAKKAKS-KLYKMPEKVKEGTVFTDLAKGQWRIGPSIGVGGFGEIYAAC 65
            |.:...:|...:..:.|..|.|| |.....:.|.||||..|.:..:|::...:........|..|
Zfish   119 PLIKDEEAKKTSPAIQSPSKCKSKKRVSSVDPVLEGTVVCDQSGKKWKLIELLWKTELDVTYGVC 183

  Fly    66 ---------------KVGEKNYDAVVKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKHGLKSLG 115
                           ::|.|            .|.||.|.:|:||.||.:.::::.:.|.|..||
Zfish   184 QANQHAESDECKYMLRLGAK------------EGHLFNEQNFHLRAAKPDAVEKWGKLHKLDFLG 236

  Fly   116 MPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYMHSNGYV 180
            :|..:..|.    .|.:||:|.|..|..|...|::....|.|..|.:||:::||..:::|...|.
Zfish   237 IPSCVGFGL----HETYRFLVFPCMGQPLQTELDEGTGSLSEKNVLQLALRLLDSLEFIHEKEYA 297

  Fly   181 HADLKAANILLGLEKGGAAQAYLVDFGLASHFVTG----DFKPDPKKMHNGTIEYTSRDAHLGV- 240
            |||:.|.||.  ::.....:.:|..||.|..|..|    :::...:..|.|.|.:.|.|:|.|.
Zfish   298 HADIHAGNIY--IKSSSHTEVFLSGFGHAFRFCPGGKHVEYRQGSRTAHQGNISFISLDSHKGAG 360

  Fly   241 PTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLF-PKGVPPPIG 304
            |:||:||:.|||.::.|:...|||  ..|......|...||.:|.::...|...: .|.....:.
Zfish   361 PSRRSDLQSLGYCMLCWMTGSLPW--SHLSHNSSSVAAEKERYMSDVPGLLTYCYKQKKASSALQ 423

  Fly   305 DFMKYVSKLTHNQEPDYDKCRSWFSSALKQL 335
            :::..|..|.:.::|||...:.....:|:::
Zfish   424 EYLCNVMALQYTEKPDYTLLKGGLQQSLQKM 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	84/312 (27%)
		SPS1	47..432	CDD:223589	81/310 (26%)
		Pol_alpha_B_N	<399..>502	CDD:285602
vrk3	NP_001013586.1	DUF4758	<9..>104	CDD:292572
		PK_VRK3	154..451	CDD:271026	84/316 (27%)
		SPS1	236..>384	CDD:223589	49/153 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D371612at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810