Protein Alignment ball and Vrk2

DIOPT Version :10

• Sequence 1: NP_651508.1
• Gene: ball / 43228
• FlyBaseID: FBgn0027889
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001388334.1
• Gene: Vrk2 / 360991
• RGDID: 1311585
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 174/481 - (36%)
• Similarity: 248/481 - (51%)
• Gaps: 66/481 - (13%)

  Fly    19 AKKAKSKLYKMPEKVKEGTVFTDLAKGQWRIGPSIGVGGFGEIYAACKVGEKNYDA--VVKCEPH 81
            |.:.|.| ||:|..:.||.:..|:...||.:|..||.||||.||.|....:...||  |:|.|..
  Rat     2 APRRKEK-YKLPVPLPEGKILDDMEGNQWALGKMIGSGGFGLIYLAFPTNKPEKDARHVIKVEYQ 65

  Fly    82 GNGPLFVEMHFYLRNAKLEDIKQFMQKHGLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTK 146
            .|||||.|:.||.|.||.|.|::::::..|..||:|.....|..:..|..:||:||.|.|.||.|
  Rat    66 ENGPLFSELKFYQRAAKRECIQKWVKQRKLDYLGVPVFYGFGLTDFKGRSYRFMVMERLGIDLQK 130

  Fly   147 FLEQNG--KRLPEGTVYRLAIQMLDVYQYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLA 209
            .|.|||  |:|   ||.:|.|:||||.:|:|.|.|||.|:||||:|||.  ....:.||.|:||:
  Rat   131 LLNQNGAFKKL---TVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY--ANPDRVYLADYGLS 190

  Fly   210 SHFV-TGDFK---PDPKKMHNGTIEYTSRDAHLGV-PTRRADLEILGYNLIEWLGAELPWVTQKL 269
            ..:. .|:.|   .||:|.||||:|:||.|||.|| |:||:|:|||||.::.||..:|||.|.
  Rat   191 YRYCPNGNHKQYHEDPRKGHNGTLEFTSLDAHKGVAPSRRSDVEILGYCMLRWLCGKLPWETN-- 253

  Fly   270 LAVPPKVQKAKEAFMDNIGES-LKTLFPKGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALK 333
            |..|..||.||...:|.:.|| ||..........:.:|..||..|.::.:|||.|        ||
  Rat   254 LENPVAVQTAKTKLLDELPESVLKWTTSGSSCRELAEFFMYVHNLAYDAKPDYQK--------LK 310

  Fly   334 QLKIPNN---GDLDFKMKPQTSSNNNLSPPGTSKAATARKAKKIDSP-VLNSSLDE-------KI 387
            ::..|:.   |.|||..|.|   ..|:..|         ..:|:||| .:....:|       |:
  Rat   311 KILNPDGVPLGPLDFSTKAQ---GVNMQTP---------IHRKVDSPKAIKKPANEFPTKYTRKV 363

  Fly   388 ---SASEDDEEEEEKSHRKKTAKKVTPSARNAKVSPLKRVADSSPPSQKRVKTEPKSTPRERAT- 448
               :.:...||:||:......:...||  .|::...::..:|:.  |:.....:.:|.||.:.:
  Rat   364 CGETRATWREEQEERRPAVLLSDLATP--ENSRTRKVREYSDTF--SEMLSFRQTQSYPRFQGSH 424

  Fly   449 -------PKASP--KPRSTPKASPKP 465
                   .:..|  |||..|:...||
  Rat   425 CKPYLDCTRRDPIRKPRPLPQYGSKP 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	131/301 (44%)
		PRK11633	<410..>471	CDD:236940	15/66 (23%)
Vrk2	NP_001388334.1	Protein Kinases, catalytic domain	16..314	CDD:473864	134/312 (43%)