DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ball and R10D12.10

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_506465.2	Gene:	R10D12.10 / 187766	WormBaseID:	WBGene00011191	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	511	Identity:	117/511 - (22%)
Similarity:	193/511 - (37%)	Gaps:	108/511 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GQWRIGPSIGVGGFGEIYAACKV--GEKNYDAVVKCEPHGNGPLFVEMHFYLRNAKL--EDIKQF 105
            |.|.   |||....|::....:|  .|...:|.:|.|                  ||  :..|:.
Worm    25 GSWF---SIGEIAKGDLSTVSRVIDSEGKIEAAMKVE------------------KLSKDSKKRS 68

  Fly   106 MQKHGLKSL-GMPYILANGSVEVNGE----KHRFIVMPRYGSDL--TKFLEQNGKRLPEGTVYRL 163
            ::|..|::| ..|:     |..:..:    .:||.||...|..|  .|.:..|  :..:.|:.||
Worm    69 IEKDVLEALRDSPH-----SAHIIEQLLIGDYRFTVMTLSGPTLGIIKHIMDN--KFSDSTILRL 126

  Fly   164 AIQMLDVYQYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHFVTGD------FKPDPK 222
            :::.|...:.:|.:|::|.||:..||.|...| .:....|:|||.|..|...|      .||..|
Worm   127 SMRTLMAIKDLHEHGFIHRDLEPFNIALSPYK-SSRNILLLDFGEARQFARNDNGKWMLRKPRDK 190

  Fly   223 KMHNGTIEYTSRDAHLGVPTRRADLEILGYNLIEW------LGAELPWV--TQKLLAVPPKVQKA 279
            ....|:.:|.|...|......|.|      :|..|      |.|.|||.  |.:.     |....
Worm   191 APFRGSDQYCSPRMHNHEEQGRVD------DLWSWLYVFVELRAFLPWTDSTSRF-----KYGPL 244

  Fly   280 KEAFMDNIGESLKTLFPKGVPPPIGDFMKYVSKLTHNQ---EPDYDKCRSWFSSALKQLKIPNNG 341
            |...:|::..|         .|.|..|...|:.|...:   .|||.|.....::.:..:.:....
Worm   245 KRELLDDLLAS---------DPFITTFCPIVTLLREGKYADRPDYGKIYEILAAKMTSMGVKWTD 300

  Fly   342 DLDFKM---KP----QTSSN--------------NNLSPPGTSKAATARKAKKIDSPVLNSSLDE 385
            .:||.:   ||    ::.||              ..:.|.|......|......:..|:..:.::
Worm   301 PMDFDLQADKPNYFSKSPSNEEVMTDEQISAAFHEQIVPGGLQYVLPANVPFYAEEKVVKKNKEK 365

  Fly   386 KISASEDDEEEEEKSHRKKTAKKVTPSARNAKVSPLKRVADSSPPSQKRVKTEPKST------PR 444
            :....:|.|:|:||...|:..|:........|....::..:.....:|::.:..|:|      |.
Worm   366 EREKEKDKEKEKEKDKEKEKEKEKEKEKDKEKEREKRKSKEKIKEKEKKMGSLEKTTERTSEAPS 430

  Fly   445 ERATPKASPKP-RSTPKASPKPQTPTAARL--RTPNAKINFSPSISLRGRPGGKTV 497
            ..|.|||.||. |:.|......:|.:.:.:  :||.:.|. .||..|..:...|||
Worm   431 TNALPKAKPKKIRTLPPKQKHTKTSSTSSVSHQTPPSPIK-KPSPKLPAQVKKKTV 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	77/310 (25%)
		SPS1	47..432	CDD:223589	94/433 (22%)
		Pol_alpha_B_N	<399..>502	CDD:285602	26/108 (24%)
R10D12.10	NP_506465.2	PKc_like	27..287	CDD:389743	76/308 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810