DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ball and T05A7.6

DIOPT Version :9

Sequence 1:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_494824.1	Gene:	T05A7.6 / 173804	WormBaseID:	WBGene00020223	Length:	758	Species:	Caenorhabditis elegans

Alignment Length:	435	Identity:	107/435 - (24%)
Similarity:	168/435 - (38%)	Gaps:	128/435 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRVAKPKAAAPAKKVVSAKKAKSKLYKMPEKVKEGTVFTDL-AKGQWRIGPSIGVGGFGEIYAA 64
            :||..|||  .||:|                |:..|.|...: |...|::...:|.||||::|..
Worm   411 LPRGEKPK--KPARK----------------KLSSGDVILGVGATDGWKVVNLLGSGGFGDVYKV 457

  Fly    65 ---------C-------KVGEKNYDAVVKCEPHGNGPLFVEMHFYLRNA------KLEDIKQFMQ 107
                     |       :.|||.|..           |.||:...::.|      |.::..:|:.
Worm   458 HRESQASNKCYALKTESEEGEKRYLR-----------LKVEVTVMMKTAEKKKDNKFKNFIEFVD 511

  Fly   108 KHGLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDL----TKFLEQNGKRLPEGTVYRLAIQML 168
            :...:.|                |.:|:||...|..|    .|:|..:   ..:.|.:.:|||.:
Worm   512 RGKCEQL----------------KCKFVVMGLVGPSLEDIRRKYLLAS---FSKHTSFNVAIQTV 557

  Fly   169 DVYQYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHFV--TGDFKPDPKKM-HNGTIE 230
            ...:.:||.||:|.|:|.||..:||:: .....|::|||:|..:|  .|..|...||: ..||:.
Worm   558 TALRDLHSLGYLHRDIKPANYAVGLDE-REDTVYMLDFGIAKLYVDENGVHKIKRKKVKFLGTLR 621

  Fly   231 YTSRDAHLGVPT-RRADLEILGYNLIEWLGAE--LPWVTQKLLAVPPKVQKAKEAF--------M 284
            |..|...:.... |:.|||...|.:.:.:...  :||   :.|..|.::.|:|..|        .
Worm   622 YACRACMMQQEQGRKDDLETWIYLVFDLMDEAHGMPW---RALCDPREILKSKNTFFATFDNFQF 683

  Fly   285 DNIGESLKTLFPKGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMKP 349
            .||.:.||            |.:.||..:.::..|||       |..|..||...| |:..|:..
Worm   684 SNILKRLK------------DLVVYVDDMQYDTTPDY-------SYILNFLKTTAN-DVGAKITK 728

  Fly   350 QTSSNNNLSPPGTSKAATARKAKKIDSPVLNSSLDEKISASEDDE 394
            :......|            |.|:.||   .|...||....:|:|
Worm   729 KLDWMGKL------------KQKEFDS---ESEKSEKKGTGDDEE 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	81/332 (24%)
		SPS1	47..432	CDD:223589	95/388 (24%)
		Pol_alpha_B_N	<399..>502	CDD:285602
T05A7.6	NP_494824.1	SPS1	100..>321	CDD:223589
		PKc_like	116..368	CDD:304357
		SPS1	439..>623	CDD:223589	54/214 (25%)
		PKc_like	440..716	CDD:304357	80/328 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810