Protein Alignment ball and TPTEP2-CSNK1E

DIOPT Version :10

• Sequence 1: NP_651508.1
• Gene: ball / 43228
• FlyBaseID: FBgn0027889
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001276841.1
• Gene: TPTEP2-CSNK1E / 102800317
• HGNCID: 53829
• Length: 416
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 122/488 - (25%)
• Similarity: 187/488 - (38%)
• Gaps: 101/488 - (20%)

  Fly    46 QWRIGPSIGVGGFGEIYAACKVGEKNYDAV-VKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKH 109
            ::|:|..||.|.||:||....:......|: ::|....:..|.:|..||          :.||
Human     8 KYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFY----------KMMQ-- 60

  Fly   110 GLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYM 174
              ..:|:|.|...|:   .|: :..:||...|..|........::....||..||.||:...:|:
Human    61 --GGVGIPSIKWCGA---EGD-YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYI 119

  Fly   175 HSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHF---VTGDFKP-DPKKMHNGTIEYTSRD 235
            ||..::|.|:|..|.|:||.|.|.. .|::|||||..:   .|....| ...|...||..|.|.:
Human   120 HSKNFIHRDVKPDNFLMGLGKKGNL-VYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASIN 183

  Fly   236 AHLGV-PTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKGV 299
            .|||: .:||.|||.|||.|:.:....|||...|......|.::..|..|....|.|    .||.
Human   184 THLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL----CKGY 244

  Fly   300 PPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMKPQTSSNNNLSPPGTSK 364
            |.....::.:...|..:.:|||...|..|.:...:.....:...|:.|               .|
Human   245 PSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM---------------LK 294

  Fly   365 AATARKAKKIDSPVLNSSLDEKISASEDDEEEEEKSHRKKTAKKVTPSARNAKVSPLKRVADSSP 429
            ...||..:.:|            ....:.|.||.....:.:|.:..|               ..|
Human   295 FGAARNPEDVD------------RERREHEREERMGQLRGSATRALP---------------PGP 332

  Fly   430 P-----SQKRVKTEP-KSTPRERATPKASPKPRSTPKASPKPQTPTAARLRTPNAKINFSPSISL 488
            |     ::.|...|| .|||..|..|..:..||:..:..         |.|..:.:::
Human   333 PTGATANRLRSAAEPVASTPASRIQPAGNTSPRAISRVD---------RERKVSMRLH------- 381

  Fly   489 RGRPGGKTVINDDLTPQ------PRSKKTYEFN 515
            ||.|.  .|.:.|||.:      |.|:.:..|:
Human   382 RGAPA--NVSSSDLTGRQEVSRIPASQTSVPFD 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	86/287 (30%)
		PRK11633	<410..>471	CDD:236940	13/66 (20%)
TPTEP2-CSNK1E	NP_001276841.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	87/296 (29%)