DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment IntS12 and mtf2

DIOPT Version :9

Sequence 1:	NP_651507.1	Gene:	IntS12 / 43227	FlyBaseID:	FBgn0039459	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001038729.1	Gene:	mtf2 / 692292	ZFINID:	ZDB-GENE-060512-94	Length:	605	Species:	Danio rerio

Alignment Length:	158	Identity:	40/158 - (25%)
Similarity:	61/158 - (38%)	Gaps:	44/158 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 LEDEANFSGRAA---TPPQQ---PIN------ADEIINLTNSPDKEPSDSVDTIADSDDGLSAVG 116
            :.|.|:....||   ||.:|   |::      .|.:.:.|....|. .:..|.:|...|||..:|
Zfish     1 MRDSASADNLAAHQNTPNRQHKSPVSLPRFPLKDGLTDTTKLAGKF-EEGQDVLARWSDGLFYLG 64

  Fly   117 IVN---------------------------TGDTGDFGDLNCCVCGEMVFTATNRLIECSKCGAM 154
            .::                           |||:|  |::.|.:|........|.::.|.|||..
Zfish    65 TISKIDKHKHRCFVIFEDQSKSWVLWKDIQTGDSG--GEMLCSICQNESSEPPNEIVICDKCGQG 127

  Fly   155 YHQECHKPPITKEEAADDQEQNWQCDTC 182
            |||.||.|.|  :.:..|.:..|.|..|
Zfish   128 YHQLCHAPVI--DSSVIDSDDKWLCRQC 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IntS12	NP_651507.1	PHD_Int12	130..182	CDD:276976	17/51 (33%)
mtf2	NP_001038729.1	TUDOR	44..95	CDD:197660	7/51 (14%)
		PHD1_MTF2	103..155	CDD:277053	18/53 (34%)
		PHD2_MTF2	202..253	CDD:277055
		Mtf2_C	556..601	CDD:290768
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4323
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900