DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment IntS12 and PHF19

DIOPT Version :9

Sequence 1:NP_651507.1 Gene:IntS12 / 43227 FlyBaseID:FBgn0039459 Length:328 Species:Drosophila melanogaster
Sequence 2:NP_001273769.1 Gene:PHF19 / 26147 HGNCID:24566 Length:599 Species:Homo sapiens


Alignment Length:70 Identity:21/70 - (30%)
Similarity:29/70 - (41%) Gaps:12/70 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 IVNTGDTGDFGDLNCCVCGEMVFTATNRLIECSKCGAMYHQECHKPPITKEEAADDQEQ----NW 177
            |.:.|..|:  :..|.:|........|.::.|.|||..|||:||.|      .|...:|    .|
Human   106 IQHAGVPGE--EPKCNICLGKTSGPLNEILICGKCGLGYHQQCHIP------IAGSADQPLLTPW 162

  Fly   178 QCDTC 182
            .|..|
Human   163 FCRRC 167

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IntS12NP_651507.1 PHD_Int12 130..182 CDD:276976 17/55 (31%)
PHF19NP_001273769.1 TUDOR 57..106 CDD:197660 21/70 (30%)
PHD1_PHF19 117..169 CDD:277054 18/57 (32%)
PHD2_PHF19 216..267 CDD:277056
Mtf2_C 550..596 CDD:316574
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4323
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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