DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lerp and M6pr

DIOPT Version :9

Sequence 1:	NP_001262996.1	Gene:	Lerp / 43223	FlyBaseID:	FBgn0051072	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_034879.2	Gene:	M6pr / 17113	MGIID:	96904	Length:	278	Species:	Mus musculus

Alignment Length:	182	Identity:	48/182 - (26%)
Similarity:	74/182 - (40%)	Gaps:	32/182 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LLLLLFCSG-------ESVAADAANQL-KFSTTECKLKE---PIYGSTFDFSGLHSDLAHVVKSM 82
            |||||....       |..:.|...:. |.|..|..|.|   |::..:|:            .::
Mouse    13 LLLLLLAVAVRESWQIEEKSCDLVGEKDKESKNEVALLERLRPLFNKSFE------------STV 65

  Fly    83 NIGGDQFE--FNICGNLSRTCNGESNVAACLKRQGKEYILGRQHELFYNNGN--MFLKYKSGAKC 143
            ..|.|.:.  |.:|...|...:| :.:....|...||.::||.:|....||:  :.|.||.|.:.
Mouse    66 GQGSDTYSYIFRVCREASNHSSG-AGLVQINKSNDKETVVGRINETHIFNGSNWIMLIYKGGDEY 129

  Fly   144 DNGTADKPNYQLHVMFSCD-YTLDAQPMHVTPYANEV--CSFYISYRTPLAC 192
            || ...|...:..||.||: :||.|....|:....:|  |.:.....:.|||
Mouse   130 DN-HCGKEQRRAVVMISCNRHTLAANFNPVSEERGKVQDCFYLFEMDSSLAC 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lerp	NP_001262996.1	CIMR	<49..143	CDD:279250	25/100 (25%)
		CIMR	157..298	CDD:279250	13/39 (33%)
		CIMR	307..435	CDD:279250
		CIMR	445..>574	CDD:279250
		CIMR	623..>666	CDD:279250
M6pr	NP_034879.2	Man-6-P_recep	1..278	CDD:280342	48/182 (26%)
M6pr	NP_034879.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	257..278
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1957
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030