DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tl and RLP1

DIOPT Version :9

Sequence 1:NP_001262995.1 Gene:Tl / 43222 FlyBaseID:FBgn0262473 Length:1117 Species:Drosophila melanogaster
Sequence 2:NP_001154318.1 Gene:RLP1 / 837251 AraportID:AT1G07390 Length:1083 Species:Arabidopsis thaliana


Alignment Length:1066 Identity:215/1066 - (20%)
Similarity:334/1066 - (31%) Gaps:395/1066 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 IQPKDYVQIMCNLTDTTDYQQLPKKLRI--------GEVDRVQMRRC--MLPGHTPIASILDYLG 123
            :|.|.|::   ||.|..:.::  :.|.|        |:..|.:..:|  .:.||. |...||.| 
plant     4 LQLKSYLK---NLVDAEEEEE--EGLSILKSWTHHEGDCCRWERVKCSDAINGHV-IGLSLDRL- 61

  Fly   124 IVSPTTLIFESDNLGMNITRQH------------------LDRLHGLKRF----RFTTRRLTH-- 164
                ..:.|||....:|::..|                  .|...|.|.|    :.||...:|  
plant    62 ----VPVAFESQTRSLNLSLLHSFPQLQSLNLSWNWFTNLSDHFLGFKSFGTLDKLTTLDFSHNM 122

  Fly   165 ----------------------------IPANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLE 200
                                        .|...|::|.||..|.|:.| ...:.|....|..:||
plant   123 FDNSIVPFLNAATSIRSLHLESNYMEGVFPPQELSNMTNLRVLNLKDNSFSFLSSQGLTDFRDLE 187

  Fly   201 SIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQL--------------------------HNLTKH 239
            .::...|.:............|||.|:|..|.|                          |.|:.|
plant   188 VLDLSFNGVNDSEASHSLSTAKLKTLDLNFNPLSDFSQLKGLESLQELQVLKLRGNKFNHTLSTH 252

  Fly   240 DFEGATSVLGIDIHDNGIEQLPH--DV--------------------------------FAHLTN 270
            ..:....:..:|:.|||...|.|  ||                                ..|..:
plant   253 VLKDLKMLQELDLSDNGFTNLDHGRDVDESRSEKRFDFREVVQKVETLWIGLRLSFQMSITHHKS 317

  Fly   271 VT------------------------------------------DINLSANLFRSLPQGLFDHNK 293
            ||                                          :::||:|...|||..| .:..
plant   318 VTVGGNGFLGLEIPTSLQVLDFKRNQLSLTHEGYLGICRLMKLRELDLSSNALTSLPYCL-GNLT 381

  Fly   294 HLNEVRLMNNRVP------LATLPSRL------------------FANQPELQILRL-------R 327
            ||..:.|.||::.      ::.|||.|                  ..||..|.:.:|       :
plant   382 HLRTLDLSNNQLNGNLSSFVSGLPSVLEYLSLLDNNFDGSFLFNSLVNQTRLTVFKLSSKVGVIQ 446

  Fly   328 AELQSLPGDLFE-HSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLT-HLPDSLFAHTT 390
            .:.:|....||: ....::|.|||..:|     ..|.||.:|..:|||:|:|| ..|..|..:.|
plant   447 VQTESSWAPLFQLKMLYLSNCSLGSTML-----GFLVHQRDLCFVDLSHNKLTGTFPTWLVKNNT 506

  Fly   391 NLTDLRLEDNLLTGI---------------SGDIFSNLGNLVTLVMSRNRLRTIDSRAFVST--- 437
            .|..:.|..|.||.:               |..|:.::...:.:|....|.....|..|..|   
plant   507 RLQTILLSGNSLTKLQLPILVHGLQVLDISSNMIYDSIQEDIGMVFPNLRFMNFSSNHFQGTIPS 571

  Fly   438 -----NGLRHLHLDHNDIDLQQPLLDI--------------MLQTQINSPFGYMHGLLTLNLRNN 483
                 ..|:.|.:..|.:..|.|::.:              .||.:|.|....:.||:.|.|..|
plant   572 SIGEMKSLQVLDMSSNGLYGQLPIMFLSGCYSLRVLKLSNNQLQGKIFSKHANLTGLVGLFLDGN 636

  Fly   484 SIIFVYNDWKNTMLQLRELDLSYN-----------NISSLGYEDLAFLSQNRLH----------- 526
            :......:.......|..||:|.|           .||.|.|   .::|.|:|.           
plant   637 NFTGSLEEGLLKSKNLTLLDISDNRFSGMLPLWIGRISRLSY---LYMSGNQLKGPFPFLRQSPW 698

  Fly   527 ---VNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRG-VHKPQYSRQ 587
               ::::||.... ::|.:|:.     .:|..:.|.:|.         |..||.| :.|......
plant   699 VEVMDISHNSFSG-SIPRNVNF-----PSLRELRLQNNE---------FTGLVPGNLFKAAGLEV 748

  Fly   588 FKLRTDRLVCSQPNVLEGTP------VRQIEPQTL----ICP------LDFSDDPRERKCPR--- 633
            ..||.:.......|.::.|.      :|....||.    ||.      ||.|.:......|.   
plant   749 LDLRNNNFSGKILNTIDQTSKLRILLLRNNSFQTYIPGKICQLSEVGLLDLSHNQFRGPIPSCFS 813

  Fly   634 ----GCNCHVRTYDKALVINCHSGNLTHVPRLP-NLHKNMQ------------------------ 669
                |...:.||  .:||.:.....:|.:|... ..|.|:.                        
plant   814 KMSFGAEQNDRT--MSLVADFDFSYITFLPHCQYGSHLNLDDGVRNGYQPKPATVVDFLTKSRYE 876

  Fly   670 ------LMELH---LENNTLLRLPSANTP----GYESVTSLHLAGNNLTSIDVDQLP--TNLTHL 719
                  |..:|   |.:|.|    |...|    ..:::.||:|:.|.||....|.:.  ..|..|
plant   877 AYQGDILRYMHGLDLSSNEL----SGEIPIEIGDLQNIRSLNLSSNRLTGSIPDSISKLKGLESL 937

  Fly   720 DISWNHLQ------MLNATVLGFLNRTMKWRSVKLSGN-PWMCDCTAKPLLLFTQDNFERIGDRN 777
            |:|.|.|.      :.:...||:||.:..    .|||. |:...       |.|.|....||  |
plant   938 DLSNNKLDGSIPPALADLNSLGYLNISYN----NLSGEIPFKGH-------LVTFDERSYIG--N 989

  Fly   778 EMMCVNAEMPTRMVELSTNDICPAEK 803
            ..:|          .|.||..|.:::
plant   990 AHLC----------GLPTNKNCISQR 1005

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TlNP_001262995.1 LRR_8 174..233 CDD:290566 16/59 (27%)
leucine-rich repeat 176..198 CDD:275380 6/22 (27%)
leucine-rich repeat 199..222 CDD:275380 3/22 (14%)
LRR_RI 216..542 CDD:238064 103/522 (20%)
LRR_8 221..281 CDD:290566 24/161 (15%)
leucine-rich repeat 223..270 CDD:275380 18/106 (17%)
leucine-rich repeat 271..294 CDD:275380 9/64 (14%)
leucine-rich repeat 295..320 CDD:275380 10/48 (21%)
leucine-rich repeat 321..343 CDD:275380 5/29 (17%)
LRR_8 342..402 CDD:290566 21/60 (35%)
leucine-rich repeat 344..367 CDD:275380 8/22 (36%)
leucine-rich repeat 368..391 CDD:275380 9/23 (39%)
LRR_8 390..450 CDD:290566 16/82 (20%)
leucine-rich repeat 392..415 CDD:275380 7/37 (19%)
leucine-rich repeat 416..439 CDD:275380 5/30 (17%)
leucine-rich repeat 440..474 CDD:275380 9/47 (19%)
leucine-rich repeat 475..498 CDD:275380 4/22 (18%)
LRR_8 477..534 CDD:290566 17/81 (21%)
leucine-rich repeat 499..520 CDD:275380 9/31 (29%)
leucine-rich repeat 523..552 CDD:275380 6/42 (14%)
LRRCT 561..619 CDD:214507 14/68 (21%)
LRRNT 631..667 CDD:214470 9/43 (21%)
leucine-rich repeat 664..693 CDD:275380 9/65 (14%)
LRR_8 669..726 CDD:290566 19/95 (20%)
leucine-rich repeat 694..715 CDD:275380 7/22 (32%)
leucine-rich repeat 716..737 CDD:275380 8/26 (31%)
LRRCT 751..800 CDD:214507 11/49 (22%)
TIR 858..996 CDD:214587
RLP1NP_001154318.1 LRR_RI 76..>274 CDD:238064 35/197 (18%)
leucine-rich repeat 84..112 CDD:275380 4/27 (15%)
leucine-rich repeat 113..136 CDD:275380 3/22 (14%)
LRR_8 135..194 CDD:290566 12/58 (21%)
leucine-rich repeat 137..161 CDD:275380 3/23 (13%)
leucine-rich repeat 162..185 CDD:275380 6/22 (27%)
leucine-rich repeat 186..209 CDD:275380 3/22 (14%)
LRR_8 209..270 CDD:290566 13/60 (22%)
leucine-rich repeat 210..231 CDD:275380 6/20 (30%)
LRR_RI 211..494 CDD:238064 55/288 (19%)
leucine-rich repeat 232..259 CDD:275380 3/26 (12%)
leucine-rich repeat 260..333 CDD:275380 11/72 (15%)
leucine-rich repeat 334..359 CDD:275380 0/24 (0%)
LRR_8 359..418 CDD:290566 16/59 (27%)
leucine-rich repeat 360..382 CDD:275380 7/22 (32%)
leucine-rich repeat 408..429 CDD:275380 1/20 (5%)
leucine-rich repeat 433..455 CDD:275380 3/21 (14%)
leucine-rich repeat 459..482 CDD:275380 8/27 (30%)
leucine-rich repeat 483..507 CDD:275380 9/23 (39%)
leucine-rich repeat 508..529 CDD:275380 5/20 (25%)
leucine-rich repeat 530..554 CDD:275380 3/23 (13%)
leucine-rich repeat 555..578 CDD:275380 4/22 (18%)
leucine-rich repeat 579..603 CDD:275380 5/23 (22%)
leucine-rich repeat 604..651 CDD:275380 9/46 (20%)
LRR_RI <638..>810 CDD:238064 36/189 (19%)
leucine-rich repeat 652..675 CDD:275380 6/22 (27%)
leucine-rich repeat 676..721 CDD:275380 9/53 (17%)
LRR_8 720..780 CDD:290566 13/68 (19%)
leucine-rich repeat 722..745 CDD:275380 8/31 (26%)
leucine-rich repeat 746..769 CDD:275380 4/22 (18%)
leucine-rich repeat 770..791 CDD:275380 5/20 (25%)
leucine-rich repeat 794..815 CDD:275380 4/20 (20%)
leucine-rich repeat 883..909 CDD:275380 7/29 (24%)
LRR_8 909..968 CDD:290566 17/62 (27%)
leucine-rich repeat 910..933 CDD:275380 7/22 (32%)
leucine-rich repeat 934..957 CDD:275380 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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